Publikationen

Publikationen aller Förderlinien

Becilli M., Metzler M., Bracaglia C., Nicolai R., Krickau T., Del Bufalo F., Rosignoli C., Marasco E., Naumann-Bartsch N., Messia V., Merli P., Pagliara D., Algeri M., Secinaro A., Cefalo MG., Diomedi Camassei F., Bertaina V., Sinibaldi M., Insalaco A., Aigner M., Leone G., Li Pira G., Gunetti M., Berg S., De Angelis B., Völkl S., Hanssens L., Müller F., Mackensen A., Quintarelli C., Schett G., De Benedetti F., Locatelli F.:
Anti-CD19 CAR T cells for pediatric patients with treatment-refractory autoimmune diseases
In: Nature Medicine (2026)
ISSN: 1078-8956
DOI: 10.1038/s41591-025-04191-8
Kopp C., Dahlmann A., Gast L., Linz P., Frielinghaus J., Breunig P., Stroebel A., Bäuerle T., Kürzinger L., Luft FC., Schiffer M., Uder M., Nagel AM.:
7-T Potassium (39K) MRI to Assess Muscle K+ Depletion in Primary Aldosteronism
In: Radiology 318 (2026), p. e252004-
ISSN: 0033-8419
DOI: 10.1148/radiol.252004

Billmann C., Schäffner I., Heppt J., Lie DC.:
Analysis of β-Catenin Signalling Activity Suggests Differential Regulation of Ontogenetically Distinct Dentate Granule Neuron Populations
In: International Journal of Developmental Neuroscience 85 (2025), Article No.: e70009
ISSN: 0736-5748
DOI: 10.1002/jdn.70009
Griesbach C., Hepp T.:
Improved confidence intervals for finite mixture regression based on resampling techniques
In: Computational Statistics (2025)
ISSN: 0943-4062
DOI: 10.1007/s00180-025-01654-x
Gómez-Zaldívar FJ., Córdova-Bahena L., Ruiz-Moreno AJ., Ceppi P., Velasco-Velázquez MA.:
In silico characterization of the interaction of AKR1B1 with the deacetylase activation domain (DAD)
In: Frontiers in Molecular Biosciences 12 (2025), Article No.: 1562206
ISSN: 2296-889X
DOI: 10.3389/fmolb.2025.1562206
Klein M., Das A., Bera SC., Anderson TK., Kocincova D., Lee HW., Wang B., Papini FS., Marecki JC., Arnold JJ., Cameron CE., Raney KD., Artsimovitch I., Götte M., Kirchdoerfer RN., Depken M., Dulin D.:
A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent
In: Nucleic Acids Research 53 (2025), Article No.: gkaf450
ISSN: 0305-1048
DOI: 10.1093/nar/gkaf450
Koopman G., Mooij P., Gaudino M., Acar RF., Irrgang P., Ruß A., Blankenstein D., Fagrouch Z., Mortier D., Böszörményi KP., Remarque EJ., Bogers WM., Verschoor EJ., Gramberg T., Tenbusch M.:
Adenoviral vector oropharyngeal spray immunization elicits mucosal immunity and protects against heterologous SARS-CoV-2 infection
In: npj Vaccines 10 (2025), Article No.: 267
ISSN: 2059-0105
DOI: 10.1038/s41541-025-01307-6
Pfeilschifter B., Martinez Vilchez A., Iqbal Z., Potue P., Fiegle D., Morhenn K., Schwoerer AP., Volk T., Seidel T.:
Cold storage of mouse hearts prior to cardiomyocyte isolation preserves electromechanical function, microstructure, and gene expression for 24 h
In: Basic research in cardiology (2025)
ISSN: 1435-1803
DOI: 10.1007/s00395-025-01131-y
Plechschmidt J., Fietkau K., Hepp T., Dietrich P., Fischer S., Krebs S., Neurath M., Dörje F., Atreya R.:
Clinical Pharmacist Counselling Improves Long-term Medication Safety and Patient-reported Outcomes in Anti-TNF-treated Patients With Inflammatory Bowel Diseases: The Prospective, Randomized AdPhaNCED Trial.
In: Inflammatory Bowel Diseases 31 (2025), p. 77-86
ISSN: 1078-0998
DOI: 10.1093/ibd/izae040
Seifert QE., Thielmann A., Bergherr E., Säfken B., Zierk J., Rauh M., Hepp T.:
Penalized regression splines in Mixture Density Networks
In: International Journal of Biostatistics (2025)
ISSN: 1557-4679
DOI: 10.1515/ijb-2023-0134
Tziridis K., Neubert B., Seehaus A., Krauß P., Schilling A., Brüggemann P., Mazurek B., Schulze H.:
Correlation of non-auditory comorbidities and hearing loss in chronic subjective tinnitus patients: a retrospective database study
In: Frontiers in Neurology 16 (2025), Article No.: 1596274
ISSN: 1664-2295
DOI: 10.3389/fneur.2025.1596274

Bierling T., Gumann A., Ottmann S., Schulz S., Weckwerth L., Thomas J., Geßner A., Wichert M., Kuwert F., Rost F., Hauke M., Freudenreich T., Mielenz D., Jäck HM., Pracht K.:
GLUT1-mediated glucose import in B cells is critical for anaplerotic balance and humoral immunity
In: Cell Reports 43 (2024), Article No.: 113739
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2024.113739
Dohnalová H., Seifert M., Matoušková E., Klein M., Stal Papini F., Lipfert J., Dulin D., Lankaš F.:
Temperature-Dependent Twist of Double-Stranded RNA Probed by Magnetic Tweezer Experiments and Molecular Dynamics Simulations
In: Journal of Physical Chemistry B 128 (2024), p. 664-675
ISSN: 1520-6106
DOI: 10.1021/acs.jpcb.3c06280
Dorner H., Stolzer I., Mattner J., Kaminski S., Leistl S., Edrich LM., Schwendner R., Hobauer J., Sebald ATE., Leikam S., Gonzalez Acera M., Düll M., Lang R., Seidel G., Seitz T., Hellerbrand C., Fuhrmann G., Distler U., Tenzer S., Eichhorn P., Vieth M., Schramm C., Arnold P., Becker C., Weidinger C., Siegmund B., Atreya R., Leppkes M., Naschberger E., Sampaziotis F., Dietrich P., Rauh M., Wirtz S., Kremer A., Neurath M., Günther C.:
Gut Pathobiont–Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in Primary Sclerosing Cholangitis–Associated Inflammatory Bowel Disease
In: Gastroenterology (2024)
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2024.06.032
Eckstein M., Matek C., Wagner P., Erber R., Büttner-Herold M., Wild PJ., Taubert H., Wach S., Sikic D., Wullich B., Geppert CI., Compérat EM., Lopez-Beltran A., Montironi R., Cheng L., van der Kwast T., Colecchia M., van Rhijn BWG., Amin MB., Netto GJ., Lehmann J., Stöckle M., Junker K., Hartmann A., Bertz S.:
Proposal for a Novel Histological Scoring System as a Potential Grading Approach for Muscle-invasive Urothelial Bladder Cancer Correlating with Disease Aggressiveness and Patient Outcomes.
In: European Urology Oncology 7 (2024), p. 128-138
ISSN: 2588-9311
DOI: 10.1016/j.euo.2023.07.011
Greiner J., Schiatti T., Kaltenbacher W., Dente M., Semenjakin A., Kok T., Fiegle D., Seidel T., Ravens U., Kohl P., Peyronnet R., Rog-Zielinska EA.:
Correction to: Consecutive-Day Ventricular and Atrial Cardiomyocyte Isolations from the Same Heart: Shifting the Cost–Benefit Balance of Cardiac Primary Cell Research (Cells, (2022), 11, 2, (233), 10.3390/cells11020233)
In: Cells 13 (2024), Article No.: 1034
ISSN: 2073-4409
DOI: 10.3390/cells13121034
Kluge V., Kappelmann-Fenzl M., Fischer S., Zimmermann T., Pommer M., Kuphal S., Boßerhoff AK.:
Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence
In: Cell Death & Disease 15 (2024), Article No.: 166
ISSN: 2041-4889
DOI: 10.1038/s41419-024-06550-8
Rauber S., Mohammadian H., Schmidkonz C., Atzinger A., Soare A., Treutlein C., Kemble S., Mahony CB., Geisthoff M., Angeli MR., Raimondo MG., Xu C., Yang KT., Lu L., Labinsky H., Saad Msa., Anchang CG., Chang J., Huang K., Kampylafka E., Knitza J., Bilyy R., Distler J., Hanlon MM., Fearon U., Veale DJ., Roemer F., Bäuerle T., Maric HM., Maschauer S., Ekici AB., Buckley CD., Croft AP., Kuwert T., Prante O., Cañete JD., Schett G., Ramming A.:
CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis
In: Nature Immunology (2024)
ISSN: 1529-2908
DOI: 10.1038/s41590-024-01774-4
Regensburger A., Eckstein M., Wetzl M., Raming R., Paulus LP., Bühler A., Nedoschill E., Danko V., Jüngert J., Wagner A., Schnell A., Rückel A., Rother U., Rompel O., Uder M., Hartmann A., Neurath M., Wölfle J., Waldner M., Hörning A., Knieling F.:
Multispectral optoacoustic tomography enables assessment of disease activity in paediatric inflammatory bowel disease
In: Photoacoustics 35 (2024), Article No.: 100578
ISSN: 2213-5979
DOI: 10.1016/j.pacs.2023.100578
Schulz-Kuhnt A., Rühle K., Javidmehr A., Döbrönti M., Biwank J., Knittel S., Neidlinger P., Leupold J., Liu L., Dedden M., Taudte RV., Geßner A., Fromm M., Mielenz D., Kreiß L., Waldner M., Schürmann S., Friedrich O., Dietel-Schor B., Lopez Posadas R., Plattner C., Zundler S., Becker C., Atreya R., Neurath M., Atreya I.:
ATP citrate lyase (ACLY)-dependent immunometabolism in mucosal T cells drives experimental colitis in vivo
In: Gut (2024), p. gutjnl-2023-330543
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2023-330543
Schwab A., Siddiqui MA., Ramesh V., Gollavilli PN., Turtos AM., Møller SS., Pinna L., Havelund JF., Rømer AMA., Ersan PG., Parma B., Marschall S., Dettmer K., Alhusayan M., Bertoglio P., Querzoli G., Mielenz D., Sahin O., Færgeman NJ., Asangani IA., Ceppi P.:
Polyol pathway-generated fructose is indispensable for growth and survival of non-small cell lung cancer
In: Cell Death and Differentiation (2024)
ISSN: 1350-9047
DOI: 10.1038/s41418-024-01415-1
Schälter F., Azizov V., Frech M., Dürholz K., Schmid E., Hendel A., Sarfati I., Maeda Y., Sokolova M., Miyagawa I., Focke K., Sarter-Zaiss K., van Baarsen LGM., Krautwald S., Schett G., Zaiss M.:
CCL19‐positive lymph node stromal cells govern the onset of inflammatory arthritis via tropomyosin receptor kinase
In: Arthritis and Rheumatology (2024)
ISSN: 2326-5191
DOI: 10.1002/art.42807
Thoma OM., Naschberger E., Kubánková M., Larafa I., Kramer V., Menchicchi B., Merkel S., Britzen-Laurent N., Jefremow A., Grützmann R., Koop K., Neufert C., Atreya R., Guck J., Stürzl M., Neurath M., Waldner M.:
p21 Prevents the Exhaustion of CD4+ T Cells Within the Antitumor Immune Response Against Colorectal Cancer
In: Gastroenterology 166 (2024), p. 284-297.e11
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2023.09.017
Wagner SJ., Matek C., Shetab Boushehri S., Boxberg M., Lamm L., Sadafi A., Winter DJ., Marr C., Peng T.:
Built to Last? Reproducibility and Reusability of Deep Learning Algorithms in Computational Pathology.
In: Modern Pathology 37 (2024)
ISSN: 0893-3952
DOI: 10.1016/j.modpat.2023.100350

Arumugam P., Ramesh V., Sampathkumar B., Perumalsamy H., Balusamy SR., Suganya K., Balraj S., Nachimuthu SK., Sundaravadivelu S.:
Integrative transcriptome analysis of triple negative breast cancer profiles for identification of druggable targets
In: Journal of biomolecular structure & dynamics (2023)
ISSN: 1538-0254
DOI: 10.1080/07391102.2022.2164795
Becker A., Babes A., Düll M., Khalil M., Kender Z., Gröner J., Namer B., Reeh P., Sauer S.:
Spontaneous activity of specific C-nociceptor subtypes from diabetic patients and mice: Involvement of reactive dicarbonyl compounds and (sensitized) transient receptor potential channel A1
In: Journal of the Peripheral Nervous System (2023)
ISSN: 1085-9489
DOI: 10.1111/jns.12546
Bergmann C., Müller F., Distler J., Györfi AH., Völkl S., Aigner M., Kretschmann S., Reimann H., Harrer T., Bayerl N., Böltz S., Wirsching A., Taubmann J., Rösler W., Spriewald B., Wacker J., Atzinger A., Uder M., Kuwert T., Mackensen A., Schett G.:
Treatment of a patient with severe systemic sclerosis (SSc) using CD19-targeted CAR T cells.
In: Annals of the Rheumatic Diseases 82 (2023), p. 1117-1120
ISSN: 0003-4967
DOI: 10.1136/ard-2023-223952
Blumenberg V., Busch G., Baumann S., Jitschin R., Iacoboni G., Gallur L., Iraola-Truchuelo J., Hoster E., Winkelmann M., Hellwig K., Schmidt C., Frölich L., Tast B., Hildebrand F., Rejeski K., Dekorsy F., Schmidkonz C., Bäuerle T., Kunz WG., Mougiakakos D., Müller F., von Bergwelt-Baildon M., Barba P., Bücklein VL., Mackensen A., Völkl S., Subklewe M.:
Early quantification of anti-CD19 CAR T cells by flow cytometry predicts response in R/R DLBCL
In: Blood Advances 7 (2023), p. 6844-6849
ISSN: 2473-9529
DOI: 10.1182/bloodadvances.2023010364
Bühler A., Brown E., Paulus LP., Eckstein M., Thoma OM., Oraiopoulou ME., Rother U., Hörning A., Hartmann A., Neurath M., Wölfle J., Friedrich O., Waldner M., Knieling F., Bohndiek SEE., Regensburger A.:
Transrectal Absorber Guide Raster-Scanning Optoacoustic Mesoscopy for Label-Free In Vivo Assessment of Colitis
In: Advanced Science (2023)
ISSN: 2198-3844
DOI: 10.1002/advs.202300564
Cao S., Li Y., Song R., Meng X., Fuchs M., Liang C., Kachler K., Meng X., Wen J., Schlötzer-Schrehardt U., Taudte V., Geßner A., Kunz M., Schleicher U., Zaiss M., Kastbom A., Chen X., Schett G., Bozec A.:
L-Arginine metabolism inhibits arthritis and inflammatory bone loss
In: Annals of the Rheumatic Diseases (2023), Article No.: ard-2022-223626
ISSN: 0003-4967
DOI: 10.1136/ard-2022-223626
Cazorla-Vázquez S., Kösters P., Bertz S., Pfister F., Daniel C., Dedden M., Zundler S., Jobst-Schwan T., Amann KU., Engel F.:
Adhesion GPCR Gpr126 (Adgrg6) Expression Profiling in Zebrafish, Mouse, and Human Kidney.
In: Cells 12 (2023), p. 1988
ISSN: 2073-4409
DOI: 10.3390/cells12151988
Chiriac MT., Hracsko Z., Becker C., Neurath M.:
STAT2 Controls Colorectal Tumorigenesis and Resistance to Anti-Cancer Drugs
In: Cancers 15 (2023), Article No.: 5423
ISSN: 2072-6694
DOI: 10.3390/cancers15225423
Chiriac MT., Hracsko Z., Günther C., Gonzalez Acera M., Atreya R., Stolzer I., Wittner L., Dressel A., Schickedanz L., Gámez Belmonte MdlR., Erkert L., Hundorfean G., Zundler S., Rath T., Vetrano S., Danese S., Sturm G., Trajanoski Z., Kühl AA., Siegmund B., Hartmann A., Wirtz S., Siebler J., Finotto S., Becker C., Neurath M.:
IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling
In: Gut (2023), Article No.: gutjnl-2023-329628
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2023-329628
Cordsmeier A., Jungnickl D., Herrmann A., Korn K., Enßer A.:
Analysis of SARS-CoV-2 Spike Protein Variants with Recombinant Reporter Viruses Created from a Bacmid System
In: International Journal of Molecular Sciences 24 (2023), Article No.: 8156
ISSN: 1422-0067
DOI: 10.3390/ijms24098156
Culemann S., Knab K., Euler M., Wegner A., Garibagaoglu H., Ackermann J., Fischer K., Kienhoefer D., Crainiciuc G., Hahn J., Grüneboom A., Nimmerjahn F., Uderhardt S., Hidalgo A., Schett G., Hoffmann M., Krönke G.:
Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes
In: Journal of Experimental Medicine 220 (2023)
ISSN: 0022-1007
DOI: 10.1084/jem.20220525
Danko V., Jüngert JM., Schüssler S., Bühler A., Klett D., Federle A., Roos A., Lochmüller H., Neurath M., Wölfle J., Trollmann R., Waldner M., Knieling F., Regensburger A., Wagner A.:
Hybrid reflected-ultrasound computed tomography versus B-mode-ultrasound for muscle scoring in spinal muscular atrophy
In: Journal of Neuroimaging (2023)
ISSN: 1051-2284
DOI: 10.1111/jon.13081
Eckstein M., Matek C., Wagner P., Erber R., Büttner-Herold M., Wild PJ., Taubert H., Wach S., Sikic D., Wullich B., Geppert CI., Compérat EM., Lopez-Beltran A., Montironi R., Cheng L., van der Kwast T., Colecchia M., van Rhijn BWG., Amin MB., Netto GJ., Lehmann J., Stöckle M., Junker K., Hartmann A., Bertz S.:
Corrigendum to "Proposal for a Novel Histological Scoring System as a Potential Grading Approach for Muscle-invasive Urothelial Bladder Cancer Correlating with Disease Aggressiveness and Patient Outcomes" [European Urology Oncology (2023)].
In: European Urology Oncology 6 (2023)
ISSN: 2588-9311
DOI: 10.1016/j.euo.2023.09.023
Fan W., Jurado-Arjona J., Alanis-Lobato G., Péron S., Berger C., Andrade-Navarro MA., Falk S., Berninger B.:
The transcriptional co-activator Yap1 promotes adult hippocampal neural stem cell activation
In: EMBO Journal (2023)
ISSN: 0261-4189
DOI: 10.15252/embj.2021110384
Firmbach D., Benz M., Kuritcyn P., Bruns V., Lang-Schwarz C., Stübs F., Merkel S., Leikauf LS., Braunschweig AL., Oldenburger A., Gloßner L., Abele N., Eck C., Matek C., Hartmann A., Geppert CI.:
Tumor–Stroma Ratio in Colorectal Cancer—Comparison between Human Estimation and Automated Assessment
In: Cancers 15 (2023), Article No.: 2675
ISSN: 2072-6694
DOI: 10.3390/cancers15102675
Gehlen-Breitbach S., Schmid T., Fröb F., Rodrian G., Weider M., Wegner M., Gölz L.:
The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development
In: International Journal of Oral Science 15 (2023), p. 16-
ISSN: 1674-2818
DOI: 10.1038/s41368-023-00222-7
Günther J., Knieling F., Träger AP., Lang W., Meyer A., Regensburger A., Wagner A., Trollmann R., Wölfle J., Klett D., Uter W., Uder M., Neurath M., Waldner M., Rother U.:
Targeting Muscular Hemoglobin Content for Classification of Peripheral Arterial Disease by Noninvasive Multispectral Optoacoustic Tomography
In: Journal of the American College of Cardiology : Cardiovascular imaging 16 (2023), p. 719-721
ISSN: 1936-878X
DOI: 10.1016/j.jcmg.2022.11.010
Hahn AM., Vogg L., Brey S., Schneider A., Schäfer S., Palmisano R., Pavlova A., Sandrock I., Tan L., Fichtner AS., Prinz I., Ravens S., Winkler T.:
A monoclonal Trd chain supports the development of the complete set of functional γδ T cell lineages
In: Cell Reports 42 (2023), p. 112558
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2023.112253
Hassel L., Fröb F., Küspert M., Hillgärtner S., Arnold P., Huang W., Kirchhoff F., Wegner M.:
Differential activity of transcription factor Sox9 in early and adult oligodendroglial progenitor cells
In: Glia (2023)
ISSN: 0894-1491
DOI: 10.1002/glia.24373
Hehr M., Sadafi A., Matek C., Lienemann P., Pohlkamp C., Haferlach T., Spiekermann K., Marr C.:
Explainable AI identifies diagnostic cells of genetic AML subtypes
In: PLOS Digital Health 2 (2023), p. e0000187
DOI: 10.1371/journal.pdig.0000187
Häselbarth L., Karow A., Mentz K., Böttcher M., Roche-Lancaster O., Krumbholz M., Jitschin R., Mougiakakos D., Metzler M.:
Effects of the STAMP-inhibitor asciminib on T cell activation and metabolic fitness compared to tyrosine kinase inhibition by imatinib, dasatinib, and nilotinib
In: Cancer Immunology, Immunotherapy (2023)
ISSN: 0340-7004
DOI: 10.1007/s00262-022-03361-8
Irianto TT., Gaipl U., Rückert M.:
Immune modulation during anti-cancer radio(immuno)therapy
In: International Review of Cell and Molecular Biology, Elsevier Inc., 2023
DOI: 10.1016/bs.ircmb.2023.05.008
Iyer K., Erkert L., Becker C.:
Know your neighbors: microbial recognition at the intestinal barrier and its implications for gut homeostasis and inflammatory bowel disease
In: Frontiers in Cell and Developmental Biology 11 (2023), Article No.: 1228283
ISSN: 2296-634X
DOI: 10.3389/fcell.2023.1228283
Klein M., Bera SC., Anderson TK., Wang B., Papini FS., Arnold JJ., Cameron CE., Depken M., Kirchdoerfer RN., Artsimovitch I., Dulin D.:
Mechanism of assembly of an elongation-competent SARS-CoV-2 replication transcription complex
In: Biophysical Journal 122 (2023), p. 171a
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2022.11.1071
Klement K., Brückner M., Bernkopf D.:
Axin phosphorylation in condensates counteracts tankyrase-mediated degradation
In: Journal of Cell Science (2023)
ISSN: 0021-9533
DOI: 10.1242/jcs.261214
Koop K., Enderle K., Hillmann M., Ruspeckhofer L., Vieth M., Sturm G., Trajanoski Z., Kuehl AA., Atreya R., Leppkes M., Baum P., Roy J., Neurath M., Martin A., Neufert C.:
Interleukin 36 receptor-inducible matrix metalloproteinase 13 mediates intestinal fibrosis
In: Frontiers in Immunology 14 (2023), Article No.: 1163198
ISSN: 1664-3224
DOI: 10.3389/fimmu.2023.1163198
Krammer S., Yang Z., Mitländer H., Grund J., Trump S., Mittler S., Zirlik S., Finotto S.:
Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells
In: Cells 12 (2023), Article No.: 129
ISSN: 2073-4409
DOI: 10.3390/cells12010129
Kraus A., Rose V., Krüger R., Sarau G., Kling L., Schiffer M., Christiansen S., Müller-Deile J.:
Characterizing Intraindividual Podocyte Morphology In Vitro with Different Innovative Microscopic and Spectroscopic Techniques
In: Cells 12 (2023), Article No.: 1245
ISSN: 2073-4409
DOI: 10.3390/cells12091245
Krug J., Rodrian G., Petter K., Yang H., Khoziainova S., Guo W., Benard A., Merkel S., Gellert S., Maschauer S., Spermann M., Waldner M., Bailey P., Pilarsky C., Liebl A., Tripal P., Christoph J., Naschberger E., Croner R., Schellerer V., Becker C., Hartmann A., Tüting T., Prante O., Grützmann R., Grivennikov SI., Stürzl M., Britzen-Laurent N.:
N-glycosylation Regulates Intrinsic IFN-γ Resistance in Colorectal Cancer: Implications for Immunotherapy
In: Gastroenterology (2023)
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2022.11.018
Langguth P., Peckert K., Beck P., Kuhnt C., Draßner C., Deinzer A., Steinkasserer A., Wild A.:
CD83 acts as immediate early response gene in activated macrophages and exhibits specific intracellular trafficking properties
In: Biochemical and Biophysical Research Communications 647 (2023), p. 37-46
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2023.01.069
Lindemann A., Roth D., Koop K., Neufert C., Zundler S., Atreya R., Neurath M., Leppkes M.:
Protective effect of the novel calcineurin inhibitor voclosporin in experimental colitis
In: Frontiers in Medicine 10 (2023), Article No.: 1177450
ISSN: 2296-858X
DOI: 10.3389/fmed.2023.1177450
Masanetz R., Baum W., Schett G., Winkler J., Süß P.:
Cellular plasticity and myeloid inflammation in the adult brain are independent of the transcriptional modulator DREAM
In: Neuroscience Letters 796 (2023), Article No.: 137061
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2023.137061
Matek C., Marr C., von Bergwelt-Baildon M., Spiekermann K.:
Künstliche Intelligenz für die computerunterstützte Leukämiediagnostik
In: Deutsche Medizinische Wochenschrift 148 (2023), p. 1108-1112
ISSN: 0012-0472
DOI: 10.1055/a-1965-7044
Matthe D., Dinkel M., Schmid B., Vogler T., Neurath M., Poeck H., Neufert C., Büttner-Herold M., Hildner K.:
Novel T cell/organoid culture system allows ex vivo modeling of intestinal graft-versus-host disease
In: Frontiers in Immunology 14 (2023), Article No.: 1253514
ISSN: 1664-3224
DOI: 10.3389/fimmu.2023.1253514
Menon R., Petrucci L., Lohrer B., Zhang J., Schulze M., Schichor C., Winner B., Winkler J., Riemenschneider MJ., Kühn R., Falk S., Karow M.:
Human Induced Pluripotent Stem Cell-Derived Pericytes as Scalable and Editable Source to Study Direct Lineage Reprogramming Into Induced Neurons
In: Cellular Reprogramming 25 (2023), p. 212-223
ISSN: 2152-4971
DOI: 10.1089/cell.2023.0008
Mitländer H., Yang Z., Krammer S., Grund J., Zirlik S., Finotto S.:
Poly I:C Pre-Treatment Induced the Anti-Viral Interferon Response in Airway Epithelial Cells
In: Viruses 15 (2023), Article No.: 2328
ISSN: 1999-4915
DOI: 10.3390/v15122328
Müller M., Herrmann A., Fujita S., Uriu K., Kruth C., Strange A., Kolberg JE., Schneider M., Ito J., Müller MA., Drosten C., Enßer A., Sato K., Sauter D.:
ORF3c is expressed in SARS-CoV-2-infected cells and inhibits innate sensing by targeting MAVS
In: EMBO Reports (2023)
ISSN: 1469-221X
DOI: 10.15252/embr.202357137
Ortiz C., Klein S., Reul WH., Magdaleno F., Groeschl S., Dietrich P., Schierwagen R., Uschner FE., Torres S., Hieber C., Meier C., Kraus N., Tyc O., Brol M., Zeuzem S., Welsch C., Poglitsch M., Hellerbrand C., Alfonso-Prieto M., Mira F., Keller UAD., Tetzner A., Moore A., Walther T., Trebicka J.:
Neprilysin-dependent neuropeptide Y cleavage in the liver promotes fibrosis by blocking NPY-receptor 1
In: Cell Reports 42 (2023)
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2023.112059
Paulus LP., Bühler A., Wagner A., Raming R., Jüngert J., Simon D., Tascilar K., Schnell A., Rother U., Eckstein M., Lang W., Hörning A., Schett G., Neurath M., Waldner M., Trollmann R., Wölfle J., Bohndiek SE., Regensburger A., Knieling F.:
Contrast-Enhanced Multispectral Optoacoustic Tomography for Functional Assessment of the Gastrointestinal Tract
In: Advanced Science (2023)
ISSN: 2198-3844
DOI: 10.1002/advs.202302562
Paulus LP., Wagner A., Buehler A., Raming R., Jüngert J., Simon D., Tascilar K., Schnell A., Günther J., Rother U., Lang W., Hörning A., Schett G., Neurath M., Wölfle J., Waldner M., Knieling F., Regensburger A.:
Multispectral optoacoustic tomography of the human intestine – temporal precision and the influence of postprandial gastrointestinal blood flow
In: Photoacoustics 30 (2023), Article No.: 100457
ISSN: 2213-5979
DOI: 10.1016/j.pacs.2023.100457
Peckert-Maier K., Langguth P., Strack A., Stich L., Mühl-Zürbes P., Kuhnt C., Drassner C., Zinser E., Wrage M., Mattner J., Steinkasserer A., Royzman D., Wild A.:
CD83 expressed by macrophages is an important immune checkpoint molecule for the resolution of inflammation
In: Frontiers in Immunology 14 (2023)
ISSN: 1664-3224
DOI: 10.3389/fimmu.2023.1085742
Rederer A., Rose V., Krüger R., Schmittutz L., Swierzy I., Fischer L., Thievessen I., Bauer J., Friedrich O., Schiffer M., Müller-Deile J.:
Partner, Neighbor, Housekeeper and Dimension: 3D versus 2D Glomerular Co-Cultures Reveal Drawbacks of Currently Used Cell Culture Models
In: International Journal of Molecular Sciences 24 (2023), Article No.: 10384
ISSN: 1422-0067
DOI: 10.3390/ijms241210384
Reimann T., Müdsam C., Schachtler C., Ince S., Sticht H., Herrmann C., Stürzl M., Kost B.:
The large GTPase AtGBPL3 links nuclear envelope formation and morphogenesis to transcriptional repression
In: Nature Plants (2023)
ISSN: 2055-0278
DOI: 10.1038/s41477-023-01400-5
Rose V., Müller-Deile J.:
Generation of Patient-Derived Podocytes from Skin Biopsies
In: Journal of Visualized Experiments 2023 (2023), Article No.: e65364
ISSN: 1940-087X
DOI: 10.3791/65364
Rubio CA., Lang-Schwarz C., Matek C., Kamaradova K., Vieth M.:
The Number of Colon Crypts in Digital Mucosal Samples: A New Independent Parameter for Diagnosing Ulcerative Colitis
In: Cancer Diagnosis & Prognosis 3-5 (2023), p. 533-537
ISSN: 2732-7787
DOI: 10.21873/cdp.10251
Sankowski R., Süß P., Benkendorff A., Böttcher C., Fernandez-Zapata C., Chhatbar C., Cahueau J., Monaco G., Gasull AD., Khavaran A., Grauvogel J., Scheiwe C., Shah MJ., Heiland DH., Schnell O., Markfeld-Erol F., Kunze M., Zeiser R., Priller J., Prinz M.:
Multiomic spatial landscape of innate immune cells at human central nervous system borders
In: Nature Medicine (2023)
ISSN: 1078-8956
DOI: 10.1038/s41591-023-02673-1
Schleier M., Lubig J., Kehl S., Hebert S., Wölfle J., van der Donk A., Bär A., Reutter HM., Hepp T., Morhart P.:
Diagnostic Utility of Interleukin-6 in Early-Onset Sepsis among Term Newborns: Impact of Maternal Risk Factors and CRP Evaluation.
In: Children 11 (2023)
ISSN: 2227-9067
DOI: 10.3390/children11010053
Schmidt A., Paudyal B., Villanueva-Hernández S., Mcnee A., Vatzia E., Carr BV., Schmidt S., Mccarron A., Martini V., Schroedel S., Thirion C., Waters R., Salguero FJ., Gerner W., Tenbusch M., Tchilian E.:
Effect of mucosal adjuvant IL-1β on heterotypic immunity in a pig influenza model
In: Frontiers in Immunology 14 (2023), Article No.: 1181716
ISSN: 1664-3224
DOI: 10.3389/fimmu.2023.1181716
Schnell A., Jüngert JM., Klett D., Hober H., Kaiser N., Ruppel R., Geppert A., Tremel C., Sobel J., Plattner E., Schmitt-Grohe S., Zirlik S., Strobel D., Neurath M., Knieling F., Rauh M., Wölfle J., Hörning A., Regensburger A.:
Increase of liver stiffness and altered bile acid metabolism after triple CFTR modulator initiation in children and young adults with cystic fibrosis
In: Liver International (2023)
ISSN: 1478-3223
DOI: 10.1111/liv.15544
Schulze L., Becker E., Dedden M., Liu L., Van Passen C., Mohamed Abdou M., Müller T., Wiendl M., Ullrich K., Atreya I., Leppkes M., Ekici AB., Kirchner P., Stürzl M., Sexton D., Palliser D., Atreya R., Siegmund B., Neurath M., Zundler S.:
Differential Effects of Ontamalimab Versus Vedolizumab on Immune Cell Trafficking in Intestinal Inflammation and Inflammatory Bowel Disease
In: Journal of Crohns & Colitis 17 (2023), p. 1817-1832
ISSN: 1873-9946
DOI: 10.1093/ecco-jcc/jjad088
Schütz M., Cordsmeier A., Wangen C., Horn A., Wyler E., Enßer A., Sticht H., Marschall M.:
The Interactive Complex between Cytomegalovirus Kinase vCDK/pUL97 and Host Factors CDK7-Cyclin H Determines Individual Patterns of Transcription in Infected Cells.
In: International Journal of Molecular Sciences 24 (2023)
ISSN: 1422-0067
DOI: 10.3390/ijms242417421
Schütz M., Wangen C., Sommerer M., Kögler M., Eickhoff J., Degenhart C., Klebl B., Naing Z., Egilmezer E., Hamilton ST., Rawlinson WD., Sticht H., Marschall M.:
Cytomegalovirus cyclin-dependent kinase ortholog vCDK/pUL97 undergoes regulatory interaction with human cyclin H and CDK7 to codetermine viral replication efficiency
In: Virus Research 335 (2023), Article No.: 199200
ISSN: 0168-1702
DOI: 10.1016/j.virusres.2023.199200
Seefried M., Hundhausen N., Kroeger I., Büttner-Herold M., Hoffmann P., Edinger M., Ullrich E., Berberich-Siebelt F., Britt WJ., Mach M., Winkler T.:
Murine cytomegalovirus reactivation concomitant with acute graft-versus-host disease is controlled by antibodies.
In: JCI Insight 8 (2023)
ISSN: 2379-3708
DOI: 10.1172/jci.insight.149648
Shi R., Reichardt M., Fiegle D., Küpfer L., Czajka T., Sun Z., Salditt T., Dendorfer A., Seidel T., Bruegmann T.:
Contractility measurements for cardiotoxicity screening with ventricular myocardial slices of pigs
In: Cardiovascular Research 119 (2023), p. 2469-2481
ISSN: 0008-6363
DOI: 10.1093/cvr/cvad141
Sinner P., Peckert-Maier K., Mohammadian H., Kuhnt C., Draßner C., Panagiotakopoulou V., Rauber S., Linnerbauer M., Haimon Z., Royzman D., Kronenberg-Versteeg D., Ramming A., Steinkasserer A., Wild A.:
Microglial expression of CD83 governs cellular activation and restrains neuroinflammation in experimental autoimmune encephalomyelitis
In: Nature Communications 14 (2023), Article No.: 4601
ISSN: 2041-1723
DOI: 10.1038/s41467-023-40370-2
Sommer J., Ehnis H., Seitz T., Schneider J., Wild A., Moceri S., Buechler C., Bozec A., Weber G., Merkel S., Beckervordersandforth R., Steinkasserer A., Schüle R., Trebicka J., Hartmann A., Boßerhoff AK., von Hörsten S., Dietrich P., Hellerbrand C.:
Four-and-a-Half LIM-Domain Protein 2 (FHL2) Induces Neuropeptide Y (NPY) in Macrophages in Visceral Adipose Tissue and Promotes Diet-Induced Obesity
In: International Journal of Molecular Sciences 24 (2023), Article No.: 14943
ISSN: 1422-0067
DOI: 10.3390/ijms241914943
Tögel L., Schubart C., Lettmaier S., Neufert C., Hoyer J., Wolff K., Moskalev E., Stöhr R., Agaimy A., Wiesmann da Silva Reis A., Wullich B., Mackensen A., Pavel ME., Beckmann M., Hartmann A., Fietkau R., Meidenbauer N., Haller F., Spörl S.:
Determinants Affecting the Clinical Implementation of a Molecularly Informed Molecular Tumor Board Recommendation: Experience from a Tertiary Cancer Center.
In: Cancers 15 (2023), Article No.: 5892
ISSN: 2072-6694
DOI: 10.3390/cancers15245892
Ullrich K., Derdau J., Baltes C., Battistella A., Rosso G., Uderhardt S., Schulze L., Liu L., Dedden M., Spocinska M., Kainka L., Kubánková M., Müller T., Schmidt NM., Becker E., Ben Brahim O., Atreya I., Finotto S., Prots I., Wirtz S., Weigmann B., Lopez Posadas R., Atreya R., Ekici AB., Lautenschläger F., Guck J., Neurath M., Zundler S.:
IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells.
In: Gut 72 (2023), p. 2081-2094
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2023-329818
Vinopal S., Dupraz S., Alfadil E., Pietralla T., Bendre S., Stiess M., Falk S., Ortega GC., Maghelli N., Tolic IM., Smejkal J., Goetz M., Bradke F.:
Centrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing brain
In: Neuron 111 (2023), p. 1241-+
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2023.01.020
Wachter F., Knieling F., Raming R., Simon D., Wölfle J., Hörning A., Neubert A., Rauh M., Regensburger A.:
Routine Surveillance of SARS-CoV-2 Serostatus in Pediatrics Allows Monitoring of Humoral Response
In: Microorganisms 11 (2023), p. 2919
ISSN: 2076-2607
DOI: 10.3390/microorganisms11122919
Weber S., Sitte S., Vögele AL., Sologub L., Wilfer A., Rath T., Nägel A., Zundler S., Franchi L., Opipari AW., Sonnewald S., Reid S., Hartmann A., Eichhorn P., Handtrack C., Weber K., Grützmann R., Neufert C., Schellerer V., Naschberger E., Ekici AB., Büttner C., Neurath M., Atreya R.:
NLRP3 Inhibition Leads to Impaired Mucosal Fibroblast Function in Patients with Inflammatory Bowel Diseases
In: Journal of Crohns & Colitis (2023), Article No.: jjad164
ISSN: 1873-9946
DOI: 10.1093/ecco-jcc/jjad164

Amon L., Dudziak D., Backer RAA., Clausen BE., Gmeiner C., Heger L., Jacobi L., Lehmann C., Probst HC., Seichter A., Tchitashvili G., Tochoedo NR., Trapaidze L., Vurnek D.:
Guidelines for DC preparation and flow cytometry analysis of mouse lymphohematopoietic tissues
In: European Journal of Immunology (2022)
ISSN: 0014-2980
DOI: 10.1002/eji.202249893
Andreev D., Kachler K., Bozec A., Schett G.:
Rheumatoid arthritis and osteoimmunology: The adverse impact of a deregulated immune system on bone metabolism
In: Bone 162 (2022), Article No.: 116468
ISSN: 8756-3282
DOI: 10.1016/j.bone.2022.116468
Battis K., Florio JB., Mante M., Lana A., Naumann I., Gauer C., Lambrecht V., Müller SK., Cobo I., Fixsen B., Kim HY., Masliah E., Glass CK., Schlachetzki JCM., Rissman RA., Winkler J., Hoffmann A.:
CSF1R-Mediated Myeloid Cell Depletion Prolongs Lifespan But Aggravates Distinct Motor Symptoms in a Model of Multiple System Atrophy
In: Journal of Neuroscience 42 (2022), p. 7673-7688
ISSN: 0270-6474
DOI: 10.1523/JNEUROSCI.0417-22.2022
Bera SC., America PPB., Maatsola S., Seifert M., Ostrofet E., Cnossen J., Spermann M., Stal Papini F., Depken M., Malinen AM., Dulin D.:
Quantitative parameters of bacterial RNA polymerase open-complex formation, stabilization and disruption on a consensus promoter
In: Nucleic Acids Research (2022)
ISSN: 0305-1048
DOI: 10.1093/nar/gkac560
Chinthapatla R., Sotoudegan M., Srivastava P., Anderson TK., Moustafa IM., Passow KT., Kennelly SA., Moorthy R., Dulin D., Feng JY., Harki DA., Kirchdoerfer RN., Cameron CE., Arnold JJ.:
Interfering with nucleotide excision by the coronavirus 3 '-to-5 ' exoribonuclease
In: Nucleic Acids Research (2022)
ISSN: 0305-1048
DOI: 10.1093/nar/gkac1177
Clausen BE., Amon L., Backer RA., Berod L., Bopp T., Brand A., Burgdorf S., Chen L., Da M., Distler U., Dress RJ., Dudziak D., Dutertre CA., Eich C., Gabele A., Geiger M., Ginhoux F., Giusiano L., Godoy GJ., Hamouda AE., Hatscher L., Heger L., Heidkamp GF., Hernandez LC., Jacobi L., Kaszubowski T., Kong WT., Lehmann C., Lopez-Lopez T., Mahnke K., Nitsche D., Renkawitz J., Reza RA., Saez PJ., Schlautmann L., Schmitt MT., Seichter A., Sielaff M., Sparwasser T., Stoitzner P., Tchitashvili G., Tenzer S., Tochoedo NR., Vurnek D., Zink F., Hieronymus T.:
Guidelines for mouse and human DC functional assays
In: European Journal of Immunology (2022)
ISSN: 0014-2980
DOI: 10.1002/eji.202249925
Desel C., Murray PJ., Lehmann C., Heger L., Christensen D., Andersen P., Mack M., Dudziak D., Lang R.:
Monocytes Elicit a Neutrophil-Independent Th1/Th17 Response Upon Immunization With a Mincle-Dependent Glycolipid Adjuvant
In: Frontiers in Immunology 13 (2022)
ISSN: 1664-3224
DOI: 10.3389/fimmu.2022.880474
Devendran R., Ramesh V., Gnanasekaran P.:
Fundamentals of cell metabolism and cancer
Elsevier, 2022
ISBN: 9780323998833
DOI: 10.1016/B978-0-323-99883-3.00001-9
Ertekin Ö., Monavari M., Krüger R., Fuentes Chandia MA., Parma B., Letort G., Tripal P., Boccaccini AR., Boßerhoff AK., Ceppi P., Kappelmann-Fenzl M., Leal-Egaña A.:
3D hydrogel-based microcapsules as an in vitro model to study tumorigenicity, cell migration and drug resistance.
In: Acta Biomaterialia (2022)
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2022.02.010
Fabian J., Dworschak GC., Waffenschmidt L., Schierbaum L., Bendixen C., Heilmann-Heimbach S., Sivalingam S., Buness A., Schwarzer N., Boemers TM., Schmiedeke E., Neser J., Leonhardt J., Kosch F., Weih S., Gielen HM., Hosie S., Kabs C., Palta M., Maerzheuser S., Bode LM., Lacher M., Schaefer FM., Stehr M., Knorr C., Ure B., Kleine K., Rolle U., Zaniew M., Phillip G., Zwink N., Jenetzky E., Reutter HM., Hilger AC.:
Genome-wide identification of disease-causing copy number variations in 450 individuals with anorectal malformations
In: European Journal of Human Genetics (2022)
ISSN: 1018-4813
DOI: 10.1038/s41431-022-01216-5
Fricke T., Großkopf AK., Enßer A., Backovic M., Hahn AS.:
Antibodies Targeting KSHV gH/gL Reveal Distinct Neutralization Mechanisms
In: Viruses 14 (2022), Article No.: 541
ISSN: 1999-4915
DOI: 10.3390/v14030541
Friedrich AC., Linz P., Nagel AM., Rosenhauer D., Horn S., Schiffer M., Uder M., Kopp C., Dahlmann A.:
Hemodialysis Patients with Cardiovascular Disease Reveal Increased Tissue Na+ Deposition
In: Kidney & Blood Pressure Research 47 (2022), p. 185-193
ISSN: 1420-4096
DOI: 10.1159/000520821
Goebel CA., Brown E., Fahlbusch F., Wagner A., Buehler A., Raupach T., Hohmann M., Späth M., Burton N., Wölfle J., Schmidt M., Hartner A., Regensburger A., Knieling F.:
High-resolution label-free mapping of murine kidney vasculature by raster-scanning optoacoustic mesoscopy: an ex vivo study
In: Molecular and Cellular Pediatrics 9 (2022), Article No.: 13
ISSN: 2194-7791
DOI: 10.1186/s40348-022-00144-0
Gámez Belmonte MdlR., Mahapatro M., Erkert L., Gonzalez Acera M., Naschberger E., Yu Y., Tena-Garitaonaindia M., Patankar J., Wagner Y., Podstawa E., Schoedel L., Bubeck M., Neurath M., Stürzl M., Becker C.:
Epithelial presenilin-1 drives colorectal tumour growth by controlling EGFR-COX2 signalling
In: Gut 72 (2022), p. 1155-1166
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2022-327323
Günther C., Winner B., Neurath M., Stappenbeck TS.:
Organoids in gastrointestinal diseases: from experimental models to clinical translation
In: Gut (2022)
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2021-326560
URL: https://gut.bmj.com/content/early/2022/05/30/gutjnl-2021-326560
Hawerkamp HC., Caoimhe F., Fallon PG., Schwartz C.:
Break on through: The role of innate immunity and barrier defence in atopic dermatitis and psoriasis
In: Skin Health and Disease 2 (2022)
ISSN: 2690-442X
DOI: 10.1002/ski2.99
Heger L., Dudziak D., Amon L., Hatscher L., Kaszubowski T., Lehmann C.:
Guidelines for DC preparation and flow cytometric analysis of human lymphohematopoietic tissues
In: European Journal of Immunology (2022)
ISSN: 0014-2980
DOI: 10.1002/eji.202249917
Heichler C., Schmied A., Enderle K., Scheibe K., Murawska M., Schmid B., Waldner M., Neurath M., Neufert C.:
Targeting STAT3 Signaling in COL1+ Fibroblasts Controls Colitis-Associated Cancer in Mice
In: Cancers 14 (2022), Article No.: 1472
ISSN: 2072-6694
DOI: 10.3390/cancers14061472
Heiß R., Tan L., Schmidt S., Regensburger A., Ewert F., Mammadova D., Bühler A., Vogel-Claussen J., Voskrebenzev A., Rauh M., Rompel O., Nagel AM., Levy S., Bickelhaupt S., May M., Uder M., Metzler M., Trollmann R., Wölfle J., Wagner A., Knieling F.:
Pulmonary Dysfunction after Pediatric COVID-19
In: Radiology (2022)
ISSN: 0033-8419
DOI: 10.1148/radiol.221250
Hepp T., Wüst W., Heiß R., May M., Kopp M., Wetzl M., Treutlein C., Uder M., Wiesmüller M.:
Apparent Diffusion Coefficient (ADC) Histogram Analysis in Parotid Gland Tumors: Evaluating a Novel Approach for Differentiation between Benign and Malignant Parotid Lesions Based on Full Histogram Distributions.
In: Diagnostics 12 (2022)
ISSN: 2075-4418
DOI: 10.3390/diagnostics12081860
Hepp T., Zierk J., Rauh M., Metzler M., Seitz S.:
Mixture density networks for the indirect estimation of reference intervals
In: BMC Bioinformatics 23 (2022), Article No.: 307
ISSN: 1471-2105
DOI: 10.1186/s12859-022-04846-0
Heym S., Mohr C., Engelbrecht HC., Fleckenstein B., Thoma-Kreß A.:
Alternative NF-kappa B Signaling Discriminates Induction of the Tumor Marker Fascin by the Viral Oncoproteins Tax-1 and Tax-2 of Human T-Cell Leukemia Viruses
In: Cancers 14 (2022)
ISSN: 2072-6694
DOI: 10.3390/cancers14030537
Huarcaya AP., Drobny S., Marques ARA., Di Spiezio A., Dobert J., Balta D., Werner C., Rizo Garza T., Gallwitz L., Bub S., Stojkovska I., Belur NR., Fogh J., Mazzulli JR., Xiang W., Fulzele A., Dejung M., Sauer M., Winner B., Rose-John S., Arnold P., Saftig P., Zunke F.:
Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.
In: Autophagy 18 (2022), p. 1127-1151
ISSN: 1554-8627
DOI: 10.1080/15548627.2022.2045534
Irrgang P., Gerling J., Kocher K., Lapuente D., Steininger P., Habenicht K., Wytopil M., Beileke S., Schäfer S., Zhong J., Ssebyatika G., Krey T., Falcone V., Schülein C., Peter AS., Nganou Makamdop K., Hengel H., Held J., Bogdan C., Überla K., Schober K., Winkler T., Tenbusch M.:
Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination
In: Science immunology (2022)
ISSN: 2470-9468
DOI: 10.1126/sciimmunol.ade2798
Jabari S., Kobow K., Pieper T., Hartlieb T., Kudernatsch M., Polster T., Bien CG., Kalbhenn T., Simon M., Hamer H., Roessler K., Feucht M., Muehlebner A., Najm I., Peixoto-Santos JE., Gil-Nagel A., Delgado RT., Aledo-Serrano A., Hou Y., Coras R., Von Deimling A., Blümcke I.:
DNA methylation-based classification of malformations of cortical development in the human brain
In: Acta Neuropathologica 143 (2022), p. 93-104
ISSN: 0001-6322
DOI: 10.1007/s00401-021-02386-0
Kalinichenko L., Gulbins E., Kornhuber J., Müller CP.:
Sphingolipid control of cognitive functions in health and disease
In: Progress in Lipid Research 86 (2022), Article No.: 101162
ISSN: 0163-7827
DOI: 10.1016/j.plipres.2022.101162
Kalinichenko L., Mühle C., Jia T., Anderheiden F., Datz M., Eberle AL., Eulenburg V., Granzow J., Hofer MJ., Hohenschild J., Huber S., Kämpf S., Kogias G., Lacatusu L., Lugmair C., Taku SM., Meixner D., Sembritzki NK., Praetner M., Rhein C., Sauer C., Scholz J., Ulrich F., Valenta F., Weigand E., Werner M., Tay N., Mc Veigh CJ., Haase J., Wang AL., Abdel-Hafiz L., Huston JP., Smaga I., Frankowska M., Filip M., Lourdusamy A., Kirchner P., Ekici AB., Marx LM., Puliparambil Suresh N., Frischknecht R., Fejtová A., Saied EM., Arenz C., Bozec A., Wank I., Kreitz S., Heß A., Bäuerle T., Ledesma MD., Mitroi DN., Miranda AM., Oliveira TG., Lenz B., Schumann G., Kornhuber J., Müller CP.:
Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males
In: Cerebral Cortex (2022)
ISSN: 1047-3211
DOI: 10.1093/cercor/bhac106
Knieling F., Cesnjevar R., Regensburger A., Wagner A., Purbojo A., Dittrich S., Münch F., Neubert A., Wölfle J., Jüngert JM., Rüffer A.:
Transfontanellar Contrast-enhanced US for Intraoperative Imaging of Cerebral Perfusion during Neonatal Arterial Switch Operation
In: Radiology 304 (2022), p. 164-173
ISSN: 0033-8419
DOI: 10.1148/radiol.212044
Kolwelter J., Kannenkeril D., Linz P., Jung S., Nagel AM., Bosch A., Ott C., Bramlage P., Nöh L., Schiffer M., Uder M., Achenbach S., Schmieder R.:
The SGLT2 inhibitor empagliflozin reduces tissue sodium content in patients with chronic heart failure: results from a placebo-controlled randomised trial
In: Clinical Research in Cardiology (2022)
ISSN: 1861-0684
DOI: 10.1007/s00392-022-02119-7
Krach F., Stemick J., Börstler T., Weiss A., Lingos I., Reischl S., Meixner H., Ploetz S., Farrell M., Hehr U., Kohl Z., Winner B., Winkler J.:
An alternative splicing modulator decreases mutant HTT and improves the molecular fingerprint in Huntington’s disease patient neurons
In: Nature Communications 13 (2022), p. 6797
ISSN: 2041-1723
DOI: 10.1038/s41467-022-34419-x
Krach F., Wheeler EC., Regensburger M., Börstler T., Wend H., Vu AQ., Wang R., Reischl S., Boldt K., Batra R., Aigner S., Ravits J., Winkler J., Yeo GW., Winner B.:
Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis
In: Acta Neuropathologica (2022)
ISSN: 0001-6322
DOI: 10.1007/s00401-022-02450-3
URL: https://link.springer.com/article/10.1007/s00401-022-02450-3#Ack1
Kreiß L., Thoma OM., Lemire S., Lechner K., Carlé BE., Dilipkumar A., Kunert T., Scheibe K., Heichler C., Merten AL., Weigmann B., Neufert C., Hildner K., Vieth M., Neurath M., Friedrich O., Schürmann S., Waldner M.:
Label-Free Characterization and Quantification of Mucosal Inflammation in Common Murine Colitis Models With Multiphoton Imaging
In: Inflammatory Bowel Diseases (2022)
ISSN: 1078-0998
DOI: 10.1093/ibd/izac114
Krämer N., Schütz M., Mato UG., Herhaus L., Marschall M., Zimmermann C.:
Recombinant Human Cytomegalovirus Expressing an Analog-Sensitive Kinase pUL97 as Novel Tool for Functional Analyses
In: Viruses 14 (2022), Article No.: 2285
ISSN: 1999-4915
DOI: 10.3390/v14102285
Köhler S., Brandl L., Strissel P., Glossner L., Ekici AB., Angeloni M., Ferrazzi F., Bahlinger V., Hartmann A., Beckmann M., Eckstein M., Strick R.:
Improved Bladder Tumor RNA Isolation from Archived Tissues Using Methylene Blue for Normalization, Multiplex RNA Hybridization, Sequencing and Subtyping
In: International Journal of Molecular Sciences 23 (2022)
ISSN: 1422-0067
DOI: 10.3390/ijms231810267
Lanfer J., Winner B., Kaindl J., Krumm L., Acera MG., Neurath M., Regensburger M., Krach F.:
Efficient and Easy Conversion of Human iPSCs into Functional Induced Microglia-like Cells
In: International Journal of Molecular Sciences 23 (2022), Article No.: 4526
ISSN: 1422-0067
DOI: 10.3390/ijms23094526
URL: https://www.mdpi.com/1422-0067/23/9/4526
Leupold L., Sigutova V., Gerasimova E., Regensburger M., Zundler S., Zunke F., Xiang W., Winner B., Prots I.:
The Quest for Anti-α-Synuclein Antibody Specificity—Lessons Learnt From Flow Cytometry Analysis
In: Frontiers in Neurology 13 (2022), Article No.: 869103
ISSN: 1664-2295
DOI: 10.3389/fneur.2022.869103
Lutz MB., Ali S., Audiger C., Autenrieth SE., Berod L., Bigley V., Cyran L., Dalod M., Dörrie J., Dudziak D., Florez-Grau G., Giusiano L., Godoy GJ., Heuer M., Krug AB., Lehmann C., Mayer CT., Naik SH., Scheu S., Schreibelt G., Segura E., Sere K., Sparwasser T., Tel J., Xu H., Zenke M.:
Guidelines for mouse and human DC generation
In: European Journal of Immunology (2022)
ISSN: 0014-2980
DOI: 10.1002/eji.202249816
Lämmerhirt L., Kappelmann-Fenzl M., Fischer S., Pommer M., Zimmermann T., Kluge V., Matthies AO., Kuphal S., Boßerhoff AK.:
Knockdown of Lamin B1 and the Corresponding Lamin B Receptor Leads to Changes in Heterochromatin State and Senescence Induction in Malignant Melanoma
In: Cells 11 (2022), Article No.: 2154
ISSN: 2073-4409
DOI: 10.3390/cells11142154
Maier E., Grottschreiber CM., Knepper I., Opdam N., Petschelt A., Loomans B., Lohbauer U.:
Evaluation of wear behavior of dental restorative materials against zirconia in vitro
In: Dental Materials 38 (2022), p. 778-788
ISSN: 0109-5641
DOI: 10.1016/j.dental.2022.04.016
Masanetz R., Winkler J., Winner B., Günther C., Süß P.:
The Gut–Immune–Brain Axis: An Important Route for Neuropsychiatric Morbidity in Inflammatory Bowel Disease
In: International Journal of Molecular Sciences 23 (2022), Article No.: 11111
ISSN: 1422-0067
DOI: 10.3390/ijms231911111
Meng X., Lin Z., Cao S., Janowska I., Sonomoto K., Andreev D., Knab K., Wen J., Knaup K., Krönke G., Rizzi M., Schett G., Bozec A., Wiesener M.:
Estrogen-mediated downregulation of HIF-1 alpha signaling in B lymphocytes influences postmenopausal bone loss
In: Bone Research 10 (2022)
ISSN: 2095-4700
DOI: 10.1038/s41413-022-00189-x
Miete C., Solis GP., Koval A., Brückner M., Katanaev VL., Behrens J., Bernkopf D.:
Gαi2-induced conductin/axin2 condensates inhibit Wnt/β-catenin signaling and suppress cancer growth
In: Nature Communications 13 (2022), p. 674-
ISSN: 2041-1723
DOI: 10.1038/s41467-022-28286-9
Mukhopadhyay S., Bera SC., Ramola K.:
Observation of two-step aggregation kinetics of amyloid-beta proteins from fractal analysis
In: Physical Biology 19 (2022)
ISSN: 1478-3967
DOI: 10.1088/1478-3975/ac6478
Neuner C., Coras R., Blümcke I., Popp A., Schlaffer SM., Wirries A., Buchfelder M., Jabari S.:
A Whole-Slide Image Managing Library Based on Fastai for Deep Learning in the Context of Histopathology: Two Use-Cases Explained
In: Applied Sciences 12 (2022)
ISSN: 2076-3417
DOI: 10.3390/app12010013
Nüssel M., Zhao Y., Knorr C., Regensburger M., Stadlbauer A., Buchfelder M., Del Vecchio A., Kinfe TM.:
Deep Brain Stimulation, Stereotactic Radiosurgery and High-Intensity Focused Ultrasound Targeting the Limbic Pain Matrix: A Comprehensive Review
In: Pain and Therapy (2022)
ISSN: 2193-8237
DOI: 10.1007/s40122-022-00381-1
Parma B., Wurdak H., Ceppi P.:
Harnessing mitochondrial metabolism and drug resistance in non-small cell lung cancer and beyond by blocking heat-shock proteins
In: Drug Resistance Updates 65 (2022)
ISSN: 1368-7646
DOI: 10.1016/j.drup.2022.100888
Probst HC., Stoitzner P., Amon L., Backer RA., Brand A., Chen J., Clausen BE., Dieckmann S., Dudziak D., Heger L., Hodapp K., Hornsteiner F., Hovav AH., Jacobi L., Ji X., Kamenjarin N., Lahl K., Lahmar I., Lakus J., Lehmann C., Ortner D., Picard M., Roberti MP., Rossnagel L., Saba Y., Schalla C., Schlitzer A., Schraml BU., Schütze K., Seichter A., Seré K., Seretis A., Sopper S., Strandt H., Sykora MM., Theobald H., Tripp CH., Zitvogel L.:
Guidelines for DC preparation and flow cytometry analysis of mouse nonlymphoid tissues
In: European Journal of Immunology (2022)
ISSN: 0014-2980
DOI: 10.1002/eji.202249819
Protze J., Naas S., Krüger R., Stöhr C., Kraus A., Grampp S., Schiffer M., Hartmann A., Wullich B., Schödel J., Wiesener M.:
The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression
In: Journal of Biological Chemistry 298 (2022), Article No.: 101699
ISSN: 0021-9258
DOI: 10.1016/j.jbc.2022.101699
Ray B., Ali I., Jana S., Mukherjee S., Pal S., Ray S., Schütz M., Marschall M.:
Antiviral Strategies Using Natural Source-Derived Sulfated Polysaccharides in the Light of the COVID-19 Pandemic and Major Human Pathogenic Viruses
In: Viruses 14 (2022), Article No.: 35
ISSN: 1999-4915
DOI: 10.3390/v14010035
Regensburger A., Wagner A., Danko V., Jüngert JM., Federle A., Klett D., Schüssler S., Buehler A., Neurath M., Roos A., Lochmüller H., Wölfle J., Trollmann R., Waldner M., Knieling F.:
Multispectral optoacoustic tomography for non-invasive disease phenotyping in pediatric spinal muscular atrophy patients
In: Photoacoustics 25 (2022), Article No.: 100315
ISSN: 2213-5979
DOI: 10.1016/j.pacs.2021.100315
Reichmann H., Csoti I., Koschel J., Lorenzl S., Schrader C., Winkler J., Wuellner U.:
Life style and Parkinson's disease
In: Journal of Neural Transmission (2022)
ISSN: 0300-9564
DOI: 10.1007/s00702-022-02509-1
Reitinger C., Ipsen Escobedo A., Hornung C., Heger L., Dudziak D., Lux A., Nimmerjahn F.:
Modulation of urelumab glycosylation separates immune stimulatory activity from organ toxicity
In: Frontiers in Immunology 13 (2022), Article No.: 970290
ISSN: 1664-3224
DOI: 10.3389/fimmu.2022.970290
Royzman D., Andreev D., Stich L., Peckert K., Wild A., Zinser E., Mühl-Zürbes P., Jones E., Adam S., Frey S., Fuchs M., Kunz M., Bäuerle T., Nagel L., Schett G., Bozec A., Steinkasserer A.:
The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis
In: Frontiers in Immunology 13 (2022)
ISSN: 1664-3224
DOI: 10.3389/fimmu.2022.936995
Royzman D., Peckert-Maier K., Stich L., König C., Wild A., Tauchi M., Ostalecki C., Kiesewetter F., Seyferth S., Lee G., Eming SA., Fuchs M., Kunz M., Stürmer EK., Peters EM., Berking C., Zinser E., Steinkasserer A.:
Soluble CD83 improves and accelerates wound healing by the induction of pro-resolving macrophages
In: Frontiers in Immunology 13 (2022), Article No.: 1012647
ISSN: 1664-3224
DOI: 10.3389/fimmu.2022.1012647
Ruß A., Wittmann S., Tsukamoto Y., Herrmann A., Deutschmann J., Lagisquet J., Enßer A., Kato H., Gramberg T.:
Nsp16 shields SARS–CoV-2 from efficient MDA5 sensing and IFIT1-mediated restriction
In: EMBO Reports 23 (2022), p. e55648
ISSN: 1469-221X
DOI: 10.15252/embr.202255648
Schmidt V., Hogan AE., Fallon PG., Schwartz C.:
Obesity-Mediated Immune Modulation: One Step Forward, (Th)2 Steps Back
In: Frontiers in Immunology 13 (2022)
ISSN: 1664-3224
DOI: 10.3389/fimmu.2022.932893
Schneider Y., Drobny A., Prots I., Zunke F., Xiang W., Seebauer L., Schneider Y., Drobny A., Ploetz S., Koudelka T., Tholey A., Prots I., Winner B., Zunke F., Winkler J., Xiang W.:
Interaction of Alpha Synuclein and Microtubule Organization Is Linked to Impaired Neuritic Integrity in Parkinson’s Patient-Derived Neuronal Cells
In: International Journal of Molecular Sciences 23 (2022), Article No.: 1812
ISSN: 1422-0067
DOI: 10.3390/ijms23031812
Schneider Y., Turan S., Koller A., Krumbiegel M., Farrell M., Plotz S., Winkler J., Xiang W.:
Generation of a homozygous and a heterozygous SNCA gene knockout human-induced pluripotent stem cell line by CRISPR/Cas9 mediated allele-specific tuning of SNCA expression
In: Stem Cell Research 65 (2022)
ISSN: 1873-5061
DOI: 10.1016/j.scr.2022.102952
Schnell A., Kohrt S., Aristodemou A., Taylor GP., Bangham CRM., Thoma-Kreß A.:
HDAC inhibitors Panobinostat and Romidepsin enhance tax transcription in HTLV-1-infected cell lines and freshly isolated patients' T-cells
In: Frontiers in Immunology 13 (2022)
ISSN: 1664-3224
DOI: 10.3389/fimmu.2022.978800
Schwartz C., Schmidt V., Deinzer A., Hawerkamp HC., Hams E., Bayerlein J., Roeger O., Bailer M., Krautz C., Elgendy A., Elshafei M., Heneghan HM., Hogan AE., O'Shea D., Fallon PG.:
Innate PD-L1 limits T cell-mediated adipose tissue inflammation and ameliorates diet-induced obesity
In: Science Translational Medicine 14 (2022), p. eabj6879-
ISSN: 1946-6234
DOI: 10.1126/scitranslmed.abj6879
Schäffner I., Wittmann MT., Vogel T., Lie DC.:
Differential vulnerability of adult neurogenic niches to dosage of the neurodevelopmental-disorder linked gene Foxg1
In: Molecular Psychiatry (2022)
ISSN: 1359-4184
DOI: 10.1038/s41380-022-01497-8
Schütz M., Müller R., Socher E., Wangen C., Full F., Wyler E., Wong DD., Scherer M., Stamminger T., Chou S., Rawlinson WD., Hamilton ST., Sticht H., Marschall M.:
Highly Conserved Interaction Profiles between Clinically Relevant Mutants of the Cytomegalovirus CDK-like Kinase pUL97 and Human Cyclins: Functional Significance of Cyclin H
In: International Journal of Molecular Sciences 23 (2022), p. 11814
ISSN: 1422-0067
DOI: 10.3390/ijms231911814
Silvin A., Uderhardt S., Piot C., Da Mesquita S., Yang K., Geirsdottir L., Mulder K., Eyal D., Liu Z., Bridlance C., Thion MS., Zhang XM., Kong WT., Deloger M., Fontes V., Weiner A., Ee R., Dress R., Hang JW., Balachander A., Chakarov S., Malleret B., Dunsmore G., Cexus O., Chen J., Garel S., Dutertre CA., Amit I., Kipnis J., Ginhoux F.:
Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration
In: Immunity 55 (2022), p. 1448-1465.e6
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2022.07.004
Stern S., Lau S., Manole A., Rosh I., Percia MM., Ben Ezer R., Shokhirev MN., Qiu F., Schafer S., Mansour AA., Mangan KP., Stern T., Ofer P., Stern Y., Mendes APD., Djamus J., Moore LR., Nayak R., Laufer SH., Aicher A., Rhee A., Wong TL., Thao Nguyen ., Linker SB., Winner B., Freitas BC., Jones E., Sagi I., Bardy C., Brice A., Winkler J., Marchetto MC., Gage FH.:
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients
In: npj Parkinson’s Disease 8 (2022), p. 103
ISSN: 2373-8057
DOI: 10.1038/s41531-022-00366-z
Taschner M., Stirnweiß A., Frankenberger R., Kramer N., Galler KM., Maier E.:
Fourteen years clinical evaluation of leucite-reinforced ceramic inlays luted using two different adhesion strategies
In: Journal of Dentistry 123 (2022), Article No.: 104210
ISSN: 0300-5712
DOI: 10.1016/j.jdent.2022.104210
Tascilar K., Fagni F., Kleyer A., Bayat S., Heidemann R., Steiger F., Krönke G., Bohr D., Ramming A., Hartmann F., Klett D., Federle A., Regensburger A., Wagner A., Knieling F., Neurath M., Schett G., Waldner M., Simon D.:
Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography
In: Rheumatology (2022)
ISSN: 1462-0324
DOI: 10.1093/rheumatology/keac346
Tisch N., Mogler C., Stojanovic A., Luck R., Korhonen EA., Ellerkmann A., Adler H., Singhal M., Schermann G., Erkert L., Patankar J., Karakatsani A., Scherr AL., Fuchs Y., Cerwenka A., Wirtz S., Koehler BC., Augustin HG., Becker C., Schmidt T., Ruiz De Almodovar C.:
Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice
In: Embo Molecular Medicine (2022)
ISSN: 1757-4676
DOI: 10.15252/emmm.202114121
Wachter F., Regensburger A., Peter AS., Knieling F., Wagner A., Simon D., Hörning A., Wölfle J., Überla K., Neubert A., Rauh M.:
Continuous monitoring of SARS-CoV-2 seroprevalence in children using residual blood samples from routine clinical chemistry
In: Clinical Chemistry and Laboratory Medicine (2022)
ISSN: 1434-6621
DOI: 10.1515/cclm-2022-0037
Wen J., Lyu P., Stolzer I., Xu J., Gießl A., Lin Z., Andreev D., Kachler K., Song R., Meng X., Cao S., Guggino G., Ciccia F., Günther C., Schett G., Bozec A.:
Epithelial HIF2 alpha expression induces intestinal barrier dysfunction and exacerbation of arthritis
In: Annals of the Rheumatic Diseases (2022)
ISSN: 0003-4967
DOI: 10.1136/annrheumdis-2021-222035
URL: https://ard.bmj.com/content/81/8/1119
Wild M., Hahn F., Brückner N., Schütz M., Wangen C., Wagner S., Sommerer M., Strobl S., Marschall M.:
Cyclin‐Dependent Kinases (CDKs) and the Human Cytomegalovirus‐Encoded CDK Ortholog pUL97 Represent Highly Attractive Targets for Synergistic Drug Combinations
In: International Journal of Molecular Sciences 23 (2022), Article No.: 2493
ISSN: 1422-0067
DOI: 10.3390/ijms23052493
Winner B., Rizo Garza T., Gebhardt L., Riedlberger J., Eberhardt E., Fester L., Alansary D., Winkler J., Turan S., Arnold P., Niemeyer B., Fischer M.:
Store-operated calcium entry is reduced in spastin-linked hereditary spastic paraplegia
In: Brain (2022)
ISSN: 0006-8950
DOI: 10.1093/brain/awac122
URL: https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awac122/6651093
(online publication)
Yu Y., Thonn V., Patankar J., Thoma OM., Waldner M., Zielinska M., Bao L., Gonzalez Acera M., Wallmueller S., Engel F., Stürzl M., Neurath M., Liebing E., Becker C.:
SMYD2 targets RIPK1 and restricts TNF-induced apoptosis and necroptosis to support colon tumor growth
In: Cell Death & Disease 13 (2022)
ISSN: 2041-4889
DOI: 10.1038/s41419-021-04483-0
Zhou X., Trinh MT., Tran Manh C., Gießl A., Bergmann C., Györfi AH., Schett G., Distler J.:
Impaired Mitochondrial Transcription Factor A Expression Promotes Mitochondrial Damage to Drive Fibroblast Activation and Fibrosis in Systemic Sclerosis
In: Arthritis and Rheumatology (2022)
ISSN: 2326-5191
DOI: 10.1002/art.42033
Zimmermann T., Pommer M., Kluge V., Chiheb C., Mühlich S., Boßerhoff AK.:
Detection of Cellular Senescence in Human Primary Melanocytes and Malignant Melanoma Cells In Vitro
In: Cells 11 (2022), Article No.: 1489
ISSN: 2073-4409
DOI: 10.3390/cells11091489
van den Hurk M., Lau S., Marchetto MC., Mertens J., Stern S., Corti O., Brice A., Winner B., Winkler J., Gage FH., Bardy C.:
Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons
In: npj Parkinson’s Disease 8 (2022), p. 134
ISSN: 2373-8057
DOI: 10.1038/s41531-022-00400-0

Aguilar C., Regensburger A., Knieling F., Wagner A., Siebenlist G., Wölfle J., Koehler H., Hörning A., Jüngert JM.:
Pediatric Buried Bumper Syndrome: Diagnostic Validity of Transabdominal Ultrasound and Artificial Intelligence
In: Ultraschall in der Medizin (2021)
ISSN: 0172-4614
DOI: 10.1055/a-1471-3039
Anni D., Weiss EM., Guhathakurta D., Akdas EY., Klueva J., Zeitler S., Andres-Alonso M., Huth T., Fejtová A.:
Aβ1-16 controls synaptic vesicle pools at excitatory synapses via cholinergic modulation of synapsin phosphorylation
In: Cellular and Molecular Life Sciences (2021)
ISSN: 1420-682X
DOI: 10.1007/s00018-021-03835-5
Arumugam P., Sampathkumar B., Perumalsamy H., Balusamy SR., Ramesh V., Sundaravadevel S.:
Synergistic effect of anethole and doxorubicin alleviates cell proliferation, cell cycle arrest, and ER stress and promotes ROS-mediated apoptosis in triple-negative breast cancer cells
In: Journal of Biochemical and Molecular Toxicology (2021)
ISSN: 1095-6670
DOI: 10.1002/jbt.22928
Bera SC., Seifert M., Kirchdoerfer RN., Van Nies P., Yibulayin W., Quack S., Papini FS., Arnold JJ., Canard B., Cameron CE., Depken M., Dulin D.:
The nucleotide addition cycle of the SARS-CoV-2 polymerase
In: Cell Reports 36 (2021), Article No.: 109650
ISSN: 2211-1247
DOI: 10.1016/j.celrep.2021.109650
Bergmann C., Hallenberger L., Chenguiti Fakhouri S., Chenguiti Fakhouri S., Merlevede B., Brandt A., Dees C., Zhu H., Zehender A., Zhou X., Schwab A., Chen CW., Györfi AH., Matei AE., Chakraborty D., Trinh-Minh T., Rauber S., Coras R., Bozec A., Kreuter A., Ziemer M., Schett G., Distler J.:
X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc)
In: Annals of the Rheumatic Diseases (2021), Article No.: annrheumdis-2020-219822
ISSN: 0003-4967
DOI: 10.1136/annrheumdis-2020-219822
Dahlmann A., Linz P., Zucker I., Haag V., Jantsch J., Dienemann T., Nagel AM., Neubert P., Rosenhauer D., Rauh M., Horn S., Müller DN., Schiffer M., Luft FC., Uder M., Kopp C.:
Reduction of Tissue Na+ Accumulation After Renal Transplantation
In: Kidney International Reports 6 (2021), p. 2338-2347
ISSN: 2468-0249
DOI: 10.1016/j.ekir.2021.06.022
Dees C., Pötter S., Fuchs M., Bergmann C., Matei AE., Györfi AH., Soare A., Ramming A., Ceppi P., Schett G., Kunz M., Distler HW.:
NCOA3 AMPLIFIES PROFIBROTIC TRANSCRIPTIONAL PROGRAMS IN SYSTEMIC SCLEROSIS
In: ANNALS OF THE RHEUMATIC DISEASES, LONDON: 2021
DOI: 10.1136/annrheumdis-2021-eular.1106
Deutschmann J., Gramberg T.:
SAMHD1 … and Viral Ways around It.
In: Viruses 13 (2021)
ISSN: 1999-4915
DOI: 10.3390/v13030395
Düll M., Wolf K., Vetter M., Dietrich P., Neurath M., Kremer A.:
Endogenous Opioid Levels Do Not Correlate With Itch Intensity and Therapeutic Interventions in Hepatic Pruritus
In: Frontiers in Medicine 8 (2021), Article No.: 641163
ISSN: 2296-858X
DOI: 10.3389/fmed.2021.641163
Enderle K., Dinkel M., Spath EM., Schmid B., Zundler S., Tripal P., Neurath M., Hildner K., Neufert C.:
Dynamic imaging of iel-iec co-cultures allows for quantification of cd103-dependent t cell migration
In: International Journal of Molecular Sciences 22 (2021), Article No.: 5148
ISSN: 1422-0067
DOI: 10.3390/ijms22105148
Faas M., Ipseiz N., Ackermann J., Culemann S., Grüneboom A., Schröder F., Rothe T., Scholtysek C., Eberhardt M., Böttcher M., Kirchner P., Stoll C., Ekici AB., Fuchs M., Kunz M., Weigmann B., Wirtz S., Lang R., Hofmann J., Vera J., Vöhringer D., Michelucci A., Mougiakakos D., Uderhardt S., Schett G., Krönke G.:
IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation
In: Immunity 54 (2021), p. 2531-2546.e5
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2021.09.010
Fiegle D., Schober M., Dittrich S., Cesnjevar R., Klingel K., Volk T., Alkassar M., Seidel T.:
Severe T-System Remodeling in Pediatric Viral Myocarditis
In: Frontiers in Cardiovascular Medicine 7 (2021)
ISSN: 2297-055X
DOI: 10.3389/fcvm.2020.624776
Fritz V., Malek L., Gaza A., Wormser L., Appel M., Kremer A., Thasler WE., Neurath M., Hellerbrand C., Boßerhoff AK., Dietrich P., Siebler J.:
Combined de‐repression of chemoresistance associated mitogen‐activated protein kinase 14 and activating transcription factor 2 by loss of microrna‐622 in hepatocellular carcinoma
In: Cancers 13 (2021), p. 1-14
ISSN: 2072-6694
DOI: 10.3390/cancers13051183
Fu J., Lehmann C., Wang X., Wahlbuhl M., Allabauer I., Wilde B., Amon L., Dolff S., Cesnjevar R., Kribben A., Wölfle J., Rascher W., Hoyer PF., Dudziak D., Witzke O., Hörning A.:
CXCR4 blockade reduces the severity of murine heart allograft rejection by plasmacytoid dendritic cell-mediated immune regulation
In: Scientific Reports 11 (2021), Article No.: 23815
ISSN: 2045-2322
DOI: 10.1038/s41598-021-03115-z
Fuentes-Chandía M., Vierling A., Kappelmann-Fenzl M., Monavari M., Letort G., Höne L., Parma B., Antara SK., Ertekin Ö., Palmisano R., Dong M., Böpple K., Boccaccini AR., Ceppi P., Boßerhoff AK., Leal-Egaña A.:
3D Spheroids Versus 3D Tumor-Like Microcapsules: Confinement and Mechanical Stress May Lead to the Expression of Malignant Responses in Cancer Cells
In: Advanced Biology 5 (2021), p. e2000349
ISSN: 2701-0198
DOI: 10.1002/adbi.202000349
Gaza A., Fritz V., Malek L., Wormser L., Treiber N., Danner J., Kremer AE., Thasler WE., Siebler J., Meister G., Neurath MF., Hellerbrand C., Boßerhoff AK., Dietrich P.:
Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11
In: Neoplasia 23 (2021), p. 502-514
ISSN: 1522-8002
DOI: 10.1016/j.neo.2021.04.001
Gaßner H., List J., Martindale C., Regensburger M., Klucken J., Winkler J., Kohl Z.:
Functional gait measures correlate to fear of falling, and quality of life in patients with Hereditary Spastic Paraplegia: A cross-sectional study
In: Clinical Neurology and Neurosurgery 209 (2021), Article No.: 106888
ISSN: 0303-8467
DOI: 10.1016/j.clineuro.2021.106888
Gollavilli PN., Parma B., Siddiqui A., Yang H., Ramesh V., Napoli F., Schwab A., Natesan R., Mielenz D., Asangani IA., Brabletz T., Pilarsky C., Ceppi P.:
The role of miR-200b/c in balancing EMT and proliferation revealed by an activity reporter
In: Oncogene (2021)
ISSN: 0950-9232
DOI: 10.1038/s41388-021-01708-6
Gonzalez Acera M., Patankar J., Diemand L., Siegmund B., Neurath M., Wirtz S., Becker C.:
Comparative Transcriptomics of IBD Patients Indicates Induction of Type 2 Immunity Irrespective of the Disease Ideotype
In: Frontiers in Medicine 8 (2021), Article No.: 664045
ISSN: 2296-858X
DOI: 10.3389/fmed.2021.664045
Gradtke AC., Mentrup T., Lehmann C., Cabrera-Cabrera F., Desel C., Okakpu D., Assmann M., Dalpke A., Schaible UE., Dudziak D., Schroder B.:
Deficiency of the Intramembrane Protease SPPL2a Alters Antimycobacterial Cytokine Responses of Dendritic Cells
In: Journal of Immunology 206 (2021), p. 164-+
ISSN: 0022-1767
DOI: 10.4049/jimmunol.2000151
Grosch M., Brunner K., Ilyaskin A., Schober M., Staudner T., Schmied D., Stumpp T., Schmidt KN., Madej MG., Dantas Pessoa T., Othmen H., Kubitza M., Osten L., De Vries U., Mair MM., Somlo S., Moser M., Kunzelmann K., Ziegler C., Härteis S., Korbmacher C., Witzgall R.:
A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts
In: Journal of Cell Science 134 (2021), Article No.: jcs259013
ISSN: 0021-9533
DOI: 10.1242/jcs.259013
Grosskopf AK., Schlagowski S., Fricke T., Enßer A., Desrosiers RC., Hahn AS.:
Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV)
In: PLoS Pathogens 17 (2021)
ISSN: 1553-7366
DOI: 10.1371/journal.ppat.1008979
Györfi AH., Matei AE., Fuchs M., Liang C., Rigau A., Hong X., Zhu H., Luber M., Bergmann C., Dees C., Ludolph I., Horch RE., Distler O., Wang J., Bengsch B., Schett G., Kunz M., Distler J.:
Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation
In: Journal of Experimental Medicine 218 (2021), Article No.: e20201916
ISSN: 0022-1007
DOI: 10.1084/jem.20201916
Günther C., Rothhammer V., Karow M., Neurath M., Winner B.:
The gut-brain axis in inflammatory bowel disease—current and future perspectives
In: International Journal of Molecular Sciences 22 (2021), Article No.: 8870
ISSN: 1422-0067
DOI: 10.3390/ijms22168870
Hamilton ST., Hahn F., Sonntag E., Marschall M., Rawlinson WD.:
A placental specific miRNA miR-517a-3p exerts anti-human cytomegalovirus activity
In: Placenta 112 (2021), p. 62-65
ISSN: 0143-4004
DOI: 10.1016/j.placenta.2021.06.013
Hamilton ST., Marschall M., Rawlinson WD.:
Investigational Antiviral Therapy Models for the Prevention and Treatment of Congenital Cytomegalovirus Infection during Pregnancy
In: Antimicrobial Agents and Chemotherapy 65 (2021)
ISSN: 0066-4804
DOI: 10.1128/AAC.01627-20
Haskamp S., Horowitz J., Oji V., Philipp S., Sticherling M., Schäkel K., Schuhmann S., Prinz JC., Burkhardt H., Behrens F., Böhm B., Köhm M., Rech J., Simon D., Schett G., Morrison K., Gerdes S., Assmann G., Nimeh A., Schuster V., Jacobi A., Weyergraf A., Reis A., Uebe S., Wilsmann-Theis D., Mößner R., Hüffmeier U.:
Genetic Analysis of MPO Variants in Four Psoriasis Subtypes in Patients from Germany
In: Journal of Investigative Dermatology (2021)
ISSN: 0022-202X
DOI: 10.1016/j.jid.2021.01.017
Hatscher L., Amon L., Heger L., Dudziak D.:
Inflammasomes in dendritic cells: Friend or foe?
In: Immunology Letters 234 (2021), p. 16-32
ISSN: 0165-2478
DOI: 10.1016/j.imlet.2021.04.002
Hatscher L., Lehmann C., Purbojo A., Onderka C., Liang C., Hartmann A., Cesnjevar R., Bruns H., Gross O., Nimmerjahn F., Burmazovic II., Kunz M., Heger L., Dudziak D.:
Select hyperactivating NLRP3 ligands enhance the TH1-and TH17-inducing potential of human type 2 conventional dendritic cells
In: Science Signaling 14 (2021), p. 1-17
ISSN: 1937-9145
DOI: 10.1126/scisignal.abe1757
URL: https://stke.sciencemag.org/content/14/680/eabe1757
Heger L., Lühr JJ., Amon L., Smith AS., Eissing N., Dudziak D.:
Six-Color Confocal Immunofluorescence Microscopy with 4-Laser Lines
In: Methods in Molecular Biology, Humana Press Inc., 2021, p. 21-30
DOI: 10.1007/978-1-0716-1593-5_2
Ittner E., Hartwig A., Elsesser O., Wüst H., Fröb F., Wedel M., Schimmel M., Tamm ER., Wegner M., Sock E.:
SoxD transcription factor deficiency in Schwann cells delays myelination in the developing peripheral nervous system
In: Scientific Reports 11 (2021), Article No.: 14044
ISSN: 2045-2322
DOI: 10.1038/s41598-021-93437-9
Jacobs B., Gebel V., Heger L., Greze V., Schild H., Dudziak D., Ullrich E.:
Characterization and Manipulation of the Crosstalk Between Dendritic and Natural Killer Cells Within the Tumor Microenvironment
In: Frontiers in Immunology 12 (2021), Article No.: 670540
ISSN: 1664-3224
DOI: 10.3389/fimmu.2021.670540
Kohrt S., Strobel S., Mann M., Sticht H., Fleckenstein B., Thoma-Kreß A.:
Characterizing the interaction between the htlv-1 transactivator tax-1 with transcription elongation factor ell2 and its impact on viral transactivation
In: International Journal of Molecular Sciences 22 (2021), Article No.: 13597
ISSN: 1422-0067
DOI: 10.3390/ijms222413597
Leppkes M., Lindemann A., Goesswein S., Paulus S., Roth D., Hartung A., Liebing E., Zundler S., Gonzalez-Acera M., Patankar J., Mascia F., Scheibe K., Hoffmann M., Uderhardt S., Schauer C., Foersch S., Neufert C., Vieth M., Schett G., Atreya R., Kuehl AA., Bleich A., Becker C., Herrmann M., Neurath M.:
Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis
In: Gut (2021)
ISSN: 0017-5749
DOI: 10.1136/gutjnl-2021-324725
Li N., Mirzakhani H., Kiefer A., Kölle J., Vuorinen T., Rauh M., Yang Z., Krammer S., Xepapadaki P., Lewandowska-Polak A., Lukkarinen H., Zhang N., Stanic B., Zimmermann T., Kowalski ML., Jartti T., Bachert C., Akdis M., Papadopoulos NG., Raby BA., Weiss ST., Finotto S.:
Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) drives the resolution of allergic asthma
In: iScience 24 (2021)
ISSN: 2589-0042
DOI: 10.1016/j.isci.2021.103163
Lu J., Meyer S.:
An endemic–epidemic beta model for time series of infectious disease proportions
In: Journal of Applied Statistics (2021)
ISSN: 0266-4763
DOI: 10.1080/02664763.2021.1962264
Mahapatro M., Erkert L., Becker C.:
Cytokine-Mediated Crosstalk between Immune Cells and Epithelial Cells in the Gut
In: Cells 10 (2021)
ISSN: 2073-4409
DOI: 10.3390/cells10010111
Mészáros L., Riemenschneider MJ., Gaßner H., Marxreiter F., von Hörsten S., Hoffmann A., Winkler J.:
Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy
In: Acta Neuropathologica Communications 9 (2021), Article No.: 68
ISSN: 2051-5960
DOI: 10.1186/s40478-021-01166-x
Mühl L., Becker E., Müller T., Atreya R., Atreya I., Neurath M., Zundler S.:
Clinical experiences and predictors of success of treatment with vedolizumab in IBD patients: a cohort study
In: BMC Gastroenterology 21 (2021), Article No.: 33
ISSN: 1471-230X
DOI: 10.1186/s12876-021-01604-z
Müller T., Becker E., Wiendl M., Schulze L., Voskens C., Kremer A., Neurath M., Zundler S., Völkl S.:
Circulating Adaptive Immune Cells Expressing the Gut Homing Marker α4β7 Integrin Are Decreased in COVID-19
In: Frontiers in Immunology 12 (2021), Article No.: 639329
ISSN: 1664-3224
DOI: 10.3389/fimmu.2021.639329
Müller-Deile J., Sopel N., Ohs A., Rose V., Gröner M., Wrede C., Hegermann J., Daniel C., Amann KU., Zahner G., Schiffer M.:
Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis.
In: Journal of the American Society of Nephrology 32 (2021), p. 2777-2794
ISSN: 1046-6673
DOI: 10.1681/ASN.2020121699
Paap EM., Müller T., Sommer K., Neurath M., Zundler S.:
Total Recall: Intestinal T-RM Cells in Health and Disease
In: Frontiers in Immunology 11 (2021)
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.623072
Parma B., Ramesh V., Gollavilli PN., Siddiqui A., Pinna L., Schwab A., Marschall S., Zhang S., Pilarsky C., Napoli F., Volante M., Urbanczyk S., Mielenz D., Schroder HD., Stemmler M., Wurdak H., Ceppi P.:
Metabolic impairment of non-small cell lung cancers by mitochondrial HSPD1 targeting
In: Journal of Experimental & Clinical Cancer Research 40 (2021)
ISSN: 1756-9966
DOI: 10.1186/s13046-021-02049-8
Patankar J., Muller TM., Kantham S., Acera MG., Mascia F., Scheibe K., Mahapatro M., Heichler C., Yu Y., Li W., Ruder B., Günther C., Leppkes M., Mathew MJ., Wirtz S., Neufert C., Kuhl AA., Paquette J., Jacobson K., Atreya R., Zundler S., Neurath M., Young RN., Becker C.:
E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis
In: Nature Cell Biology 23 (2021), p. 796-807
ISSN: 1465-7392
DOI: 10.1038/s41556-021-00708-8
Patankar JV., Lehmann M., Kühl AA., Atreya R., Becker C., Gonzalez-Acera M., Schmitt H., Gamez-Belmonte R., Mahapatro M., Diemand L., Hartmann L., Mascia F., Hracsko Z., Thonn V., Schödel L., Zielinska M., Yu Y., Erkert L., Li W., Zeitler M., Ruder B., Ganzleben I., Günther C., Vöhringer D., Zundler S., Neurath M., Siegmund B., Chiriac MT.:
Severe Acute Respiratory Syndrome Coronavirus 2 Attachment Receptor Angiotensin-Converting Enzyme 2 Is Decreased in Crohn's Disease and Regulated By Microbial and Inflammatory Signaling
In: Gastroenterology 160 (2021), p. 925-928.e4
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2020.10.021
Pommer M., Kuphal S., Boßerhoff AK.:
Amphiregulin Regulates Melanocytic Senescence
In: Cells 10 (2021)
ISSN: 2073-4409
DOI: 10.3390/cells10020326
Prax K., Schmiedel K., Hepp T., Schlager H., Friedland K.:
Preventive Care in Type 2 Diabetes: Results of a Randomized, Controlled Trial in Community Pharmacies
In: Diabetes Care 44 (2021), p. E157-E159
ISSN: 0149-5992
DOI: 10.2337/dc20-2319
Regensburger A., Brown E., Krönke G., Waldner M., Knieling F.:
Optoacoustic Imaging in Inflammation
In: Biomedicines 9 (2021), Article No.: 483
ISSN: 2227-9059
DOI: 10.3390/biomedicines9050483
Regensburger D., Tenkerian C., Pürzer V., Schmid B., Wohlfahrt T., Stolzer I., Lopez Posadas R., Günther C., Waldner M., Becker C., Sticht H., Petter K., Flierl C., Gass T., Thoenissen T., Geppert CI., Britzen-Laurent N., Meniel VS., Ramming A., Stürzl M., Naschberger E.:
Matricellular Protein SPARCL1 Regulates Blood Vessel Integrity and Antagonizes Inflammatory Bowel Disease
In: Inflammatory Bowel Diseases (2021)
ISSN: 1078-0998
DOI: 10.1093/ibd/izaa346
Rhein C., Hepp T., Kraus O., von Majewski K., Lieb M., Rohleder N., Erim Y.:
Interleukin-6 secretion upon acute psychosocial stress as a potential predictor of psychotherapy outcome in posttraumatic stress disorder
In: Journal of Neural Transmission (2021)
ISSN: 0300-9564
DOI: 10.1007/s00702-021-02346-8
Schmitt H., Neurath M., Atreya R.:
Role of the IL23/IL17 Pathway in Crohn’s Disease
In: Frontiers in Immunology 12 (2021), Article No.: 622934
ISSN: 1664-3224
DOI: 10.3389/fimmu.2021.622934
Schnell A., Kohrt S., Thoma-Kreß A.:
Latency reversing agents: Kick and kill of htlv-1?
In: International Journal of Molecular Sciences 22 (2021), Article No.: 5545
ISSN: 1422-0067
DOI: 10.3390/ijms22115545
Schütz M., Steingruber M., Socher E., Müller R., Wagner S., Kögel M., Sticht H., Marschall M.:
Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97
In: Viruses 13 (2021), p. 1248
ISSN: 1999-4915
DOI: 10.3390/v13071248
Seifert M., Bera SC., Van Nies P., Kirchdoerfer RN., Shannon A., Le TTN., Meng X., Xia H., Wood JM., Harris LD., Papini FS., Arnold JJ., Almo S., Grove TL., Shi PY., Xiang Y., Canard B., Depken M., Cameron CE., Dulin D.:
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective
In: eLife 10 (2021)
ISSN: 2050-084X
DOI: 10.7554/eLife.70968
Seitz T., Hackl C., Freese K., Dietrich P., Mahli A., Thasler RM., Thasler WE., Lang SA., Boßerhoff AK., Hellerbrand C.:
Xanthohumol, a prenylated chalcone derived from hops, inhibits growth and metastasis of melanoma cells
In: Cancers 13 (2021), p. 1-12
ISSN: 2072-6694
DOI: 10.3390/cancers13030511
Stehr A., Wang G., Demmler R., Stemmler M., Straube J., Tripal P., Schmid B., Geppert CI., Hartmann A., Munoz LE., Schoen J., Völkl S., Merkel S., Becker C., Schett G., Grützmann R., Naschberger E., Herrmann M., Stürzl M.:
Neutrophil extracellular traps drive epithelial‐mesenchymal transition of human colon cancer
In: Journal of Pathology 256 (2021), p. 455-467
ISSN: 0022-3417
DOI: 10.1002/path.5860
Stürzl M., Kunz M., Krug SM., Naschberger E.:
Angiocrine Regulation of Epithelial Barrier Integrity in Inflammatory Bowel Disease
In: Frontiers in Medicine 8 (2021), Article No.: 643607
ISSN: 2296-858X
DOI: 10.3389/fmed.2021.643607
Vonbrunn E., Ries T., Söllner S., Müller-Deile J., Büttner M., Amann KU., Daniel C.:
Multiplex gene analysis reveals T-cell and antibody-mediated rejection-specific upregulation of complement in renal transplants
In: Scientific Reports 11 (2021), Article No.: 15464
ISSN: 2045-2322
DOI: 10.1038/s41598-021-94954-3
Wagner A., Danko V., Federle A., Klett D., Simon D., Heiß R., Jüngert JM., Uder M., Schett G., Neurath M., Wölfle J., Waldner M., Trollmann R., Regensburger A., Knieling F.:
Precision of handheld multispectral optoacoustic tomography for muscle imaging
In: Photoacoustics 21 (2021), Article No.: 100220
ISSN: 2213-5979
DOI: 10.1016/j.pacs.2020.100220
Weindl L., Atreya I., Dietrich P., Neubeck S., Neurath M., Pavel ME.:
Targeted inhibition of the WEE1 kinase as a novel therapeutic strategy in neuroendocrine neoplasms
In: Endocrine-Related Cancer 28 (2021), p. 605-620
ISSN: 1351-0088
DOI: 10.1530/ERC-20-0500
Wiendl M., Becker E., Müller T., Voskens C., Neurath M., Zundler S.:
Targeting Immune Cell Trafficking – Insights From Research Models and Implications for Future IBD Therapy
In: Frontiers in Immunology 12 (2021), Article No.: 656452
ISSN: 1664-3224
DOI: 10.3389/fimmu.2021.656452
Wild M., Kicuntod J., Seyler L., Wangen C., Bertzbach LD., Conradie AM., Kaufer BB., Wagner S., Michel D., Eickhoff J., Tsogoeva S., Bäuerle T., Hahn F., Marschall M.:
Combinatorial drug treatments reveal promising anticytomegaloviral profiles for clinically relevant pharmaceutical kinase inhibitors (PKIs)
In: International Journal of Molecular Sciences 22 (2021), p. 1-20
ISSN: 1422-0067
DOI: 10.3390/ijms22020575
Wirries A., Geiger F., Hammad A., Redder A., Oberkircher L., Ruchholtz S., Blümcke I., Jabari S.:
Combined Artificial Intelligence Approaches Analyzing 1000 Conservative Patients with Back Pain-A Methodological Pathway to Predicting Treatment Efficacy and Diagnostic Groups
In: Diagnostics 11 (2021)
ISSN: 2075-4418
DOI: 10.3390/diagnostics11111934
Zehender A., Li YN., Lin NY., Stefanica A., Nüchel J., Chen CW., Hsu HH., Zhu H., Ding X., Huang J., Shen L., Györfi AH., Soare A., Rauber S., Bergmann C., Ramming A., Plomann M., Eckes B., Schett G., Distler J.:
TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy
In: Nature Communications 12 (2021), Article No.: 4404
ISSN: 2041-1723
DOI: 10.1038/s41467-021-24601-y
Zhang Y., Shen L., Dreißigacker K., Zhu H., Trinh MT., Meng X., Tran Manh C., Dees C., Matei AE., Chen CW., Ditschkowski M., Krauss S., Winkler J., Wolff D., Ziemer M., Beilhack A., Karrer S., Herr W., Mackensen A., Schett G., Spriewald BM., Distler J.:
Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease
In: Blood 137 (2021), p. 2403-2416
ISSN: 0006-4971
DOI: 10.1182/blood.2020008720
Zunke F., Winner B., Richter F., Caraveo G.:
Editorial: Intracellular Mechanisms of α-Synuclein Processing.
In: Frontiers in Cell and Developmental Biology 9 (2021), Article No.: ARTN 752378
ISSN: 2296-634X
DOI: 10.3389/fcell.2021.752378

Abu-Khousa M., Fiegle D., Sommer ST., Minabari G., Milting H., Heim C., Weyand M., Tomasi R., Dendorfer A., Volk T., Seidel T.:
The Degree of t-System Remodeling Predicts Negative Force-Frequency Relationship and Prolonged Relaxation Time in Failing Human Myocardium
In: Frontiers in Physiology 11 (2020), Article No.: 182
ISSN: 1664-042X
DOI: 10.3389/fphys.2020.00182
Allner C., Melde M., Becker E., Fuchs F., Mühl L., Klenske E., Müller L., Morgenstern N., Fietkau K., Hirschmann S., Atreya R., Atreya I., Neurath M., Zundler S.:
Baseline levels of dynamic CD4+ T cell adhesion to MAdCAM-1 correlate with clinical response to vedolizumab treatment in ulcerative colitis: a cohort study
In: BMC Gastroenterology 20 (2020), p. 103-
ISSN: 1471-230X
DOI: 10.1186/s12876-020-01253-8
Amon L., Hatscher L., Heger L., Dudziak D., Lehmann C.:
Harnessing the complete repertoire of conventional dendritic cell functions for cancer immunotherapy
In: Pharmaceutics 12 (2020), p. 1-83
ISSN: 1999-4923
DOI: 10.3390/pharmaceutics12070663
Amon L., Lehmann C., Heger L., Heidkamp GF., Dudziak D.:
The ontogenetic path of human dendritic cells
In: Molecular Immunology 120 (2020), p. 122-129
ISSN: 0161-5890
DOI: 10.1016/j.molimm.2020.02.010
Andreev D., Liu M., Kachler K., Llerins Perez M., Kirchner P., Kölle J., Gießl A., Rauber S., Song R., Aust O., Grüneboom A., Kleyer A., Cañete JD., Ekici AB., Ramming A., Finotto S., Schett G., Bozec A.:
Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis
In: Annals of the Rheumatic Diseases (2020)
ISSN: 0003-4967
DOI: 10.1136/annrheumdis-2020-218902
Andreev D., Liu M., Weidner D., Kachler K., Faas M., Grüneboom A., Schlötzer-Schrehardt U., Munoz LE., Steffen U., Grötsch B., Killy B., Krönke G., Luebke AM., Niemeier A., Wehrhan F., Lang R., Schett G., Bozec A.:
Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin
In: Journal of Clinical Investigation 130 (2020), p. 4811-4830
ISSN: 0021-9738
DOI: 10.1172/JCI134214
Bardenbacher M., Ruder B., Britzen-Laurent N., Naschberger E., Becker C., Palmisano R., Stürzl M., Tripal P.:
Investigating Intestinal Barrier Breakdown in Living Organoids
In: Journal of Visualized Experiments (2020)
ISSN: 1940-087X
DOI: 10.3791/60546
URL: https://www.jove.com/video/60546/investigating-intestinal-barrier-breakdown-in-living-organoids
Bera SC., Seifert M., Ostrofet E., Spermann M., Papini FS., Malinen AM., Dulin D.:
Monovalent Salt Dependence of the Bacterial RNA Polymerase Open Complex Dynamics
64th Annual Meeting of the Biophysical-Society (San Diego, CA, 15. Februar 2020 - 19. Februar 2020)
In: BIOPHYSICAL JOURNAL, CAMBRIDGE: 2020
DOI: 10.1016/j.bpj.2019.11.2971
Boscardin SB., Dudziak D., Muenz C., Rosa DS.:
Harnessing the Participation of Dendritic Cells in Immunity and Tolerance
In: Frontiers in Immunology 11 (2020), Article No.: 595841
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.595841
Börstler T., Wend H., Krumbiegel M., Kavyanifar A., Wiesmann da Silva Reis A., Lie DC., Winner B., Turan S.:
CRISPR/Cas9 mediated generation of human ARID1B heterozygous knockout hESC lines to model Coffin-Siris syndrome
In: Stem Cell Research 47 (2020), Article No.: 101889
ISSN: 1873-5061
DOI: 10.1016/j.scr.2020.101889
Cabrita I., Kraus A., Scholz JK., Skoczynski K., Schreiber R., Kunzelmann K., Buchholz B.:
Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo
In: Nature Communications 11 (2020), Article No.: 4320
ISSN: 2041-1723
DOI: 10.1038/s41467-020-18104-5
Cerrone F., Pozner T., Siddiqui A., Ceppi P., Winner B., Rajendiran M., Babu R., Ibrahim HS., Rodriguez BJ., Winkler J., Murphy KJ., O'Connor KE.:
Polyhydroxyphenylvalerate/polycaprolactone nanofibers improve the life-span and mechanoresponse of human IPSC-derived cortical neuronal cells
In: Materials Science and Engineering C 111 (2020), Article No.: 110832
ISSN: 0928-4931
DOI: 10.1016/j.msec.2020.110832
Chakraborty D., Zhu H., Juengel A., Summa L., Li YN., Matei AE., Zhou X., Huang J., Thuong Trinh-Minh ., Chen CW., Lafyatis R., Dees C., Bergmann C., Soare A., Luo H., Ramming A., Schett G., Distler O., Distler J.:
Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis
In: Science Translational Medicine 12 (2020)
ISSN: 1946-6234
DOI: 10.1126/scitranslmed.aaz5506
Cosma-Grigorov A., Meixner H., Mrochen A., Wirtz S., Winkler J., Marxreiter F.:
Changes in Gastrointestinal Microbiome Composition in PD: A Pivotal Role of Covariates
In: Frontiers in Neurology 11 (2020), Article No.: 1041
ISSN: 1664-2295
DOI: 10.3389/fneur.2020.01041
Couté Y., Kraut A., Zimmermann C., Büscher N., Hesse AM., Bruley C., De Andrea M., Wangen C., Hahn F., Marschall M., Plachter B.:
Mass spectrometry-based characterization of the virion proteome, phosphoproteome, and associated kinase activity of human cytomegalovirus
In: Microorganisms 8 (2020), Article No.: 820
ISSN: 2076-2607
DOI: 10.3390/microorganisms8060820
Dietrich P., Wormser L., Fritz V., Seitz T., de Maria M., Schambony A., Kremer A., Günther C., Itzel T., Thasler WE., Teufel A., Trebicka J., Hartmann A., Neurath M., von Hörsten S., Boßerhoff AK., Hellerbrand C.:
Molecular cross-talk between Y5-receptor and neuropeptide Y drives liver cancer
In: Journal of Clinical Investigation 130 (2020), p. 2509-2526
ISSN: 0021-9738
DOI: 10.1172/JCI131919
Dietschmann A., Schruefer S., Krappmann S., Vöhringer D.:
Th2 cells promote eosinophil-independent pathology in a murine model of allergic bronchopulmonary aspergillosis
In: European Journal of Immunology (2020)
ISSN: 0014-2980
DOI: 10.1002/eji.201948411
Donhauser N., Socher E., Millen S., Heym S., Sticht H., Thoma-Kreß A.:
Transfer of htlv-1 p8 and gag to target t-cells depends on vasp, a novel interaction partner of p8
In: PLoS Pathogens 16 (2020), Article No.: e1008879
ISSN: 1553-7366
DOI: 10.1371/journal.ppat.1008879
Fiegle D., Volk T., Seidel T.:
Isolation of human ventricular cardiomyocytes from vibratome-cut myocardial slices
In: Journal of Visualized Experiments 2020 (2020), Article No.: e61167
ISSN: 1940-087X
DOI: 10.3791/61167
Fliedner A., Kirchner P., Wiesener A., van de Beek I., Waisfisz Q., van Haelst M., Scott DA., Lalani SR., Rosenfeld JA., Azamian MS., Xia F., Dutra-Clarke M., Martinez-Agosto JA., Lee H., Nelson SF., Grody WW., Deignan JL., Kang SH., Arboleda VA., Senaratne TN., Dorrani N., Dutra-Clarke MS., Kianmahd J., Hinkamp FL., Neustadt AM., Fogel BL., Quintero-Rivera F., Noh GJ., Lippa N., Alkelai A., Aggarwal V., Agre KE., Gavrilova R., Mirzaa GM., Straussberg R., Cohen R., Horist B., Krishnamurthy V., McWalter K., Juusola J., Davis-Keppen L., Ohden L., van Slegtenhorst M., de Man SA., Ekici AB., Gregor A., van de Laar I., Zweier C.:
Variants in SCAF4 Cause a Neurodevelopmental Disorder and Are Associated with Impaired mRNA Processing
In: American Journal of Human Genetics (2020)
ISSN: 0002-9297
DOI: 10.1016/j.ajhg.2020.06.019
Gamez-Belmonte R., Erkert L., Wirtz S., Becker C.:
The Regulation of Intestinal Inflammation and Cancer Development by Type 2 Immune Responses
In: International Journal of Molecular Sciences 21 (2020)
ISSN: 1422-0067
DOI: 10.3390/ijms21249772
Gebhardt L., Kichko T., Fischer MJ., Reeh P.:
TRPA1-dependent calcium transients and CGRP release in DRG neurons require extracellular calcium
In: The Journal of Cell Biology 219 (2020)
ISSN: 0021-9525
DOI: 10.1083/jcb.201702151
Grosche L., Knippertz I., König C., Royzman D., Wild A., Zinser E., Sticht H., Muller Y., Steinkasserer A., Lechmann M.:
The CD83 Molecule – An Important Immune Checkpoint
In: Frontiers in Immunology 11 (2020), Article No.: 721
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.00721
Heger L., Hofer TP., Bigley V., de Vries IJM., Dalod M., Dudziak D., Ziegler-Heitbrock L.:
Subsets of CD1c+ DCs: Dendritic Cell Versus Monocyte Lineage
In: Frontiers in Immunology 11 (2020), Article No.: 559166
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.559166
Kara S., Amon L., Lühr J., Nimmerjahn F., Dudziak D., Lux A.:
Impact of Plasma Membrane Domains on IgG Fc Receptor Function
In: Frontiers in Immunology 11 (2020), Article No.: 1320
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.01320
Klingler A., Regensburger D., Tenkerian C., Britzen-Laurent N., Hartmann A., Stürzl M., Naschberger E.:
Species-, organ- and cell-type-dependent expression of SPARCL1 in human and mouse tissues.
In: PLoS ONE 15 (2020), Article No.: e0233422
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0233422
Knieling F., Rüffer A., Cesnjevar R., Regensburger A., Purbojo A., Dittrich S., Münch F., Neubert A., Meyer S., Strobel D., Rascher W., Wölfle J., Jüngert JM.:
Transfontanellar Contrast-Enhanced Ultrasound for Monitoring Brain Perfusion During Neonatal Heart Surgery
In: Circulation: Cardiovascular Imaging 13 (2020), p. e010073-
ISSN: 1941-9651
DOI: 10.1161/CIRCIMAGING.119.010073
Koch A., Ebert EV., Seitz T., Dietrich P., Berneburg M., Boßerhoff AK., Hellerbrand C.:
Characterization of glycolysis-related gene expression in malignant melanoma
In: Pathology Research and Practice 216 (2020), Article No.: 152752
ISSN: 0344-0338
DOI: 10.1016/j.prp.2019.152752
Kogias G., Zheng F., Kalinichenko L., Kornhuber J., Alzheimer C., Mielenz D., Müller CP.:
Swiprosin1/EFhd2 is involved in the monoaminergic and locomotor responses of psychostimulant drugs
In: Journal of Neurochemistry (2020), Article No.: e14959
ISSN: 0022-3042
DOI: 10.1111/jnc.14959
Kühn H., Kappes L., Wolf K., Gebhardt L., Neurath M., Reeh P., Fischer MJ., Kremer A.:
Complementary roles of murine NaV1.7, NaV1.8 and NaV1.9 in acute itch signalling
In: Scientific Reports 10 (2020), Article No.: 2326
ISSN: 2045-2322
DOI: 10.1038/s41598-020-59092-2
Lampert A., Bennett DL., McDermott LA., Neureiter A., Eberhardt E., Winner B., Zenke M.:
Human sensory neurons derived from pluripotent stem cells for disease modelling and personalized medicine
In: Neurobiology of pain (Cambridge, Mass.) 8 (2020), Article No.: 100055
ISSN: 2452-073X
DOI: 10.1016/j.ynpai.2020.100055
Lauer V., Grampp S., Platt J., Lafleur V., Lombardi O., Choudhry H., Kranz F., Hartmann A., Wullich B., Yamamoto A., Coleman ML., Ratcliffe PJ., Mole DR., Schödel J.:
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)-mediated induction of the long noncoding RNA NICI
In: Journal of Biological Chemistry 295 (2020), p. 4065-4078
ISSN: 0021-9258
DOI: 10.1074/jbc.RA119.009827
Liebig J., Kuphal S., Boßerhoff AK.:
Hurdling senescence: hur breaks braf-induced senescence in melanocytes and supports melanoma growth
In: Cancers 12 (2020), Article No.: 1299
ISSN: 2072-6694
DOI: 10.3390/cancers12051299
Linck-Paulus L., Hellerbrand C., Boßerhoff AK., Dietrich P.:
Dissimilar Appearances Are Deceptive-Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma
In: Cells 9 (2020)
ISSN: 2073-4409
DOI: 10.3390/cells9010114
Lu J., Meyer S.:
Forecasting flu activity in the united states: Benchmarking an endemic-epidemic beta model
In: International Journal of Environmental Research and Public Health 17 (2020), Article No.: 1381
ISSN: 1660-4601
DOI: 10.3390/ijerph17041381
Luhr JJ., Alex N., Amon L., Krater M., Kubankova M., Sezgin E., Lehmann C., Heger L., Heidkamp GF., Smith AS., Zaburdaev V., Böckmann R., Levental I., Dustin ML., Eggeling C., Dudziak D., Guck J.:
Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition
In: Frontiers in Immunology 11 (2020), Article No.: 590121
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.590121
Marxreiter F., Buttler U., Gaßner H., Gandor F., Gladow T., Eskofier B., Winkler J., Ebersbach G., Klucken J.:
The Use of Digital Technology and Media in German Parkinson's Disease Patients
In: Journal of Parkinson's Disease 10 (2020), p. 717-727
ISSN: 1877-7171
DOI: 10.3233/JPD-191698
Millen S., Meretuk L., Göttlicher T., Schmitt S., Fleckenstein B., Thoma-Kreß A.:
A novel positive feedback-loop between the HTLV-1 oncoprotein Tax and NF-κB activity in T-cells
In: Retrovirology 17 (2020), p. 30-
ISSN: 1742-4690
DOI: 10.1186/s12977-020-00538-w
Mühlberger M., Unterweger H., Band J., Lehmann C., Heger L., Dudziak D., Alexiou C., Lee G., Janko C.:
Loading of Primary Human T Lymphocytes with Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Does Not Impair Their Activation after Polyclonal Stimulation
In: Cells 9 (2020)
ISSN: 2073-4409
DOI: 10.3390/cells9020342
Ostrofet E., Papini FS., Dulin D.:
High spatiotemporal resolution data from a custom magnetic tweezers instrument
In: Data in Brief 30 (2020), Article No.: 105397
ISSN: 2352-3409
DOI: 10.1016/j.dib.2020.105397
Ostrofet E., Papini FS., Johnson B., Arnold JJ., Cameron CE., Dulin D.:
Single-Molecule Magnetic Tweezers Characterization of MTERF1 as a Directional Roadblock
64th Annual Meeting of the Biophysical-Society (San Diego, CA, 15. Februar 2020 - 19. Februar 2020)
In: BIOPHYSICAL JOURNAL, CAMBRIDGE: 2020
DOI: 10.1016/j.bpj.2019.11.573
Patankar JV., Becker C.:
Cell death in the gut epithelium and implications for chronic inflammation
In: Nature Reviews Gastroenterology & Hepatology (2020)
ISSN: 1759-5045
DOI: 10.1038/s41575-020-0326-4
Ramesh V., Brabletz T., Ceppi P.:
Targeting EMT in Cancer with Repurposed Metabolic Inhibitors
In: Trends in Cancer (2020)
ISSN: 2405-8033
DOI: 10.1016/j.trecan.2020.06.005
Regensburger A., Wagner A., Claussen J., Waldner M., Knieling F.:
Shedding light on pediatric diseases: multispectral optoacoustic tomography at the doorway to clinical applications.
In: Molecular and Cellular Pediatrics 7 (2020)
ISSN: 2194-7791
DOI: 10.1186/s40348-020-00095-4
Regensburger A., Wagner A., Hanslik G., Schuessler SC., Fahlbusch F., Wölfle J., Juengert J., Trollmann R., Knieling F.:
Ultra-high-frequency ultrasound in patients with spinal muscular atrophy: A retrospective feasibility study
In: Muscle & Nerve 61 (2020), p. E18-E21
ISSN: 0148-639X
DOI: 10.1002/mus.26796
Ruder B., Becker C.:
At the Forefront of the Mucosal Barrier: The Role of Macrophages in the Intestine
In: Cells 9 (2020)
ISSN: 2073-4409
DOI: 10.3390/cells9102162
Ruder B., Günther C., Stürzl M., Neurath M., Cesarman E., Ballon G., Becker C.:
Viral FLIP blocks Caspase-8 driven apoptosis in the gut in vivo
In: PLoS ONE 15 (2020), Article No.: e0228441
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0228441
Safi W., Kraus A., Grampp S., Schödel J., Buchholz B.:
Macrophage migration inhibitory factor is regulated by HIF-1α and cAMP and promotes renal cyst cell proliferation in a macrophage-independent manner
In: Journal of Molecular Medicine 98 (2020), p. 1547-1559
ISSN: 0946-2716
DOI: 10.1007/s00109-020-01964-1
Saunders SP., Floudas A., Moran T., Byrne CM., Rooney MD., Fahy CM., Geoghegan JA., Iwakura Y., Fallon PG., Schwartz C.:
Dysregulated skin barrier function in Tmem79 mutant mice promotes IL-17A-dependent spontaneous skin and lung inflammation
In: Allergy (2020)
ISSN: 0105-4538
DOI: 10.1111/all.14488
Schierwagen R., Dietrich P., Klein S., Uschner FE., Ortiz C., Tyc O., Torres S., Hellerbrand C., Sauerbruch T., Trebicka J.:
β-Arrestin2 is increased in liver fibrosis in humans and rodents
In: Proceedings of the National Academy of Sciences of the United States of America 117 (2020), p. 27082-27084
ISSN: 0027-8424
DOI: 10.1073/pnas.2014337117
Schilling A., Tomasello R., Henningsen-Schomers MR., Zankl A., Surendra K., Haller M., Karl V., Uhrig P., Maier A., Krauß P.:
Analysis of continuous neuronal activity evoked by natural speech with computational corpus linguistics methods
In: Language, Cognition and Neuroscience (2020)
ISSN: 2327-3798
DOI: 10.1080/23273798.2020.1803375
Schütz M., Thomas M., Wangen C., Wagner S., Rauschert L., Errerd T., Kießling M., Sticht H., Milbradt J., Marschall M.:
The peptidyl-prolyl cis/trans isomerase Pin1 interacts with three early regulatory proteins of human cytomegalovirus
In: Virus Research 285 (2020), Article No.: 198023
ISSN: 0168-1702
DOI: 10.1016/j.virusres.2020.198023
Seifert M., van Nies P., Papini FS., Arnold JJ., Poranen MM., Cameron CE., Depken M., Dulin D.:
Temperature controlled high-throughput magnetic tweezers show striking difference in activation energies of replicating viral RNA-dependent RNA polymerases
In: Nucleic Acids Research 48 (2020), p. 5591-5602
ISSN: 0305-1048
DOI: 10.1093/nar/gkaa233
Seitz T., Freese K., Dietrich P., Thasler WE., Boßerhoff AK., Hellerbrand C.:
Fibroblast Growth Factor 9 is expressed by activated hepatic stellate cells and promotes progression of hepatocellular carcinoma
In: Scientific Reports 10 (2020), Article No.: 4546
ISSN: 2045-2322
DOI: 10.1038/s41598-020-61510-4
Siddiqui A., Ceppi P.:
A non-proliferative role of pyrimidine metabolism in cancer
In: Molecular Metabolism 35 (2020), Article No.: 100962
ISSN: 2212-8778
DOI: 10.1016/j.molmet.2020.02.005
Siddiqui MA., Gollavilli PN., Ramesh V., Parma B., Schwab A., Vazakidou ME., Natesan R., Saatci O., Rapa I., Bironzo P., Schuhwerk H., Asangani IA., Sahin O., Volante M., Ceppi P.:
Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer
In: British Journal of Cancer (2020)
ISSN: 0007-0920
DOI: 10.1038/s41416-020-01095-x
Simon D., Tascilar K., Krönke G., Kleyer A., Zaiss M., Heppt F., Meder C., Atreya R., Klenske E., Dietrich P., Abdullah A., Kliem T., Corte G., Morf H., Leppkes M., Kremer A., Pachowsky M., Schuch F., Ronneberger M., Kleinert S., Meier C., Hueber A., Manger K., Manger B., Berking C., Tenbusch M., Überla K., Sticherling M., Neurath M., Schett G., Ramming A.:
Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion
In: Nature Communications 11 (2020), Article No.: 3774
ISSN: 2041-1723
DOI: 10.1038/s41467-020-17703-6
Straub J., Gregor A., Sauerer T., Fliedner A., Distel L., Suchy C., Ekici AB., Ferrazzi F., Zweier C.:
Genetic interaction screen for severe neurodevelopmental disorders reveals a functional link between Ube3a and Mef2 in Drosophila melanogaster
In: Scientific Reports 10 (2020), Article No.: 1204
ISSN: 2045-2322
DOI: 10.1038/s41598-020-58182-5
Tannig P., Peter AS., Lapuente D., Klessing S., Damm D., Tenbusch M., Überla K., Temchura V.:
Modulation of vaccine-induced HIV-1-specific immune responses by co-electroporation of PD-L1 encoding DNA
In: Vaccines 8 (2020), Article No.: 27
ISSN: 2076-393X
DOI: 10.3390/vaccines8010027
Tohumeken S., Böttcher M., Stoll A., Loschinski R., Panagiotidis K., Braun M., Saul D., Baur A., Bruns H., Mackensen A., Jitschin R., Mougiakakos D., Völkl S., Baur R.:
Palmitoylated Proteins on AML-Derived Extracellular Vesicles Promote Myeloid-Derived Suppressor Cell Differentiation via TLR2/Akt/mTOR Signaling
In: Cancer Research 80 (2020), p. 3663-3676
ISSN: 0008-5472
DOI: 10.1158/0008-5472.CAN-20-0024
Weider M., Schröder A., Docheva D., Rodrian G., Enderle I., Seidel CL., Andreev D., Wegner M., Bozec A., Deschner J., Kirschneck C., Proff P., Gölz L.:
A human periodontal ligament fibroblast cell line as a new model to study periodontal stress
In: International Journal of Molecular Sciences 21 (2020), p. 1-10
ISSN: 1422-0067
DOI: 10.3390/ijms21217961
Zhang Y., Zhu H., Layritz F., Luo H., Wohlfahrt T., Chen CW., Soare A., Bergmann C., Ramming A., Groeber F., Reuter C., Fornasini G., Soukhareva N., Schreiber B., Ramamurthy S., Amann KU., Schett G., Distler J.:
Recombinant Adenosine Deaminase Ameliorates Inflammation, Vascular Disease, and Fibrosis in Preclinical Models of Systemic Sclerosis
In: Arthritis and Rheumatology (2020)
ISSN: 2326-5191
DOI: 10.1002/art.41259

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