J89: Adrian Regensburger, Department of Pediatric and Adolescent Medicine
MSOT imaging of strictures in Crohn’s disease
Main Research: Medical Engineering
Term: 01.01.2021 – 30.09.2023 (bonus time until 31.03.2024)
Intestinal strictures are a major disease burden in Crohn’s disease. Conventional cross-sectional imaging modalities are currently not able to differentiate between inflammatory and fibrotic components of strictures. This would be essential for the initiation of the appropriate therapy. In a translational approach we want to investigate whether optoacoustic imaging can be used to quantify hemoglobin as a sign of inflammation and collagen as a sign of fibrosis in murine and human intestine.
PD Dr. Adrian Regensburger
phonen: +49 9131 85-33118
J103: Eva Maier, Department of Operative Dentistry and Periodontology
Predicting clinical longevity of dental materials
Main Research: Medical Engineeringv
Term: 16.12.2022 – 15.06.2025
With the rapid translation of emerging material processing technologies for tooth restoration, there is an urgent need for reliable laboratory testing systems that accurately predict the clinical longevity of new materials. The current proposal aims to 1) develop a novel in-vitro wear testing model that demonstrates accurate preclinical predictability of longitudinal clinical trial data and 2) explore the suitability of modern 3D-printing processes for dental material application.
Dr. Eva Maier