Förderjahre
- Arkenau, Catrin Leonie
Medizinische Klinik 1
Bile Acid–driven Enteric Nervous System dysfunction as a novel driver of mucosal inflammation - Aslan, Hasan
Molekular-Neurologische Abteilung
The role of lysosomal function in astrocytes in Parkinson’s Disease - Bajbouj, Susan
Medizinische Klinik 3
Role of Skin–Joint Crosstalk in Bone Homeostasis in Psoriatic Arthritis - Becker, Mani
Institut für Anatomie
Analyzing the temporo-spatial expression pattern of the transcription factor SOX11 in early human
development. - Denzler, Manuel
Kinder- und Jugendklinik
HBM-EV-Mediated Epithelial Regeneration in Age-Stratified Neonatal Intestinal Organoids - Eldeeb, Fatma
Institut für Biochemie-Lehrstuhl für Biochemie u. Mol. Medizin
Analysis of Lipid Metabolism in Dormant Malignant Melanoma Cells - Englich, Tim
Kinder- und Jugendklinik
Characterization of Imaging Biomarkers in a Caterpillar Model of Intestinal Inflammation. - Farez, Nayla Yael
Institut für Biomedizin des Alterns – Lehrstuhl für Innere Medizin (Geriatrie)
Einfluss der Dimerisierung von löslichem PD-L1 bei autoimmuner Entzündung des Zentralnervensystems - Heiligers, Tim
Kinder- und Jugendklinik
Quantitative Assessment of Neurovascular Remodeling in Neonates Using Ultrasound Localization Microscopy - Herrmann, Elena Simone
Neurologische Klinik
AHR–HIF Crosstalk as a Key Mechanism of Hypoxia-Driven Glial Activation in Multiple Sclerosis - Kraft, Levin
Molekular-Pneumologische Abteilung
Improvement of current immunotherapy (PD-1 Blockade) in lung cancer: the role of IL-15 - Legenstein, Amelie
Translational-Immunologische Abteilung
QPCT/L-Mediated Immunoregulation: Enzymatic Activity and Therapeutic Opportunity in Neuroblastoma - Lückhoff, Peter
Hautklinik
Therapy Monitoring of Prostate Cancer Patients measuring Protease Activity in Plasma extracellular Vesicles (pEV) - Marterer, Anna Christina
Medizinische Klinik 1
Microbial Extracellular Vesicles as Modulators of CD4+ T Cell Responses in Multiple Sclerosis - Miller, Paul
Medizinische Klinik 1
Establishment of an ex vivo model for the preclinical analysis of VAV1 modulators in human colon explants - Nölp, Mirjam
Frauenklinik
Transplacental Extracellular Vesicles as Mediators of Perinatal Immune Priming - Oltmanns, Jakob
Nephropathologische Abteilung
Elucidating the role of DMPK in NE-MTOC formation - Pink, Melanie
Medizinische Klinik 1
Unravelling the role of mEVs in Microbiota-driven Relapse mechanisms of Rheumatoid Arthritis - Pönisch, Lilly
Hals-Nasen-Ohren-Klinik F
rom Nanoparticle Uptake to Cellular Magnetism: A Framework for Engineering Magnetic Cell Properties - Ragab, Omnya
Strahlenklinik
Increased Sensitivity to Ionizing Radiation in Patients with Cancer and Hashimoto´s thyroiditis. - Rode, Louisa
MCO – Medizincampus Oberfranken
Heat shock-induced enhancer RNA induction and transcriptome remodeling in K562 cells - Scherbel, Janina
Medizinische Klinik 1
Metabolomic Fingerprints as Predictive Biomarkers in Crohn’s Disease - Schoen, Meike
Lehrstuhl für Anatomie
Impact of Transcription Factor EB (TFEB) overexpression on the generation of adult born dentate
gyrus granule neurons - Söltner, Alexander
Institut für Experimentelle und Klinische Pharmakologie und Toxikologie
Deorphanization and Substrate Identification of the Human Transporter OAT10 (SLC22A13) by
Untargeted Metabolomics and in vitro Uptake Assays - Studeneer, Marcel
Neurochirurgische Klinik
Contribution of astrocytes subtypes in the hippocampus to the pathology of Alzheimer’s disease - Tashi, Laert
Medizinische Klinik 1
Role of telomere shortening in CD4+ T cells during their antitumor response to colorectal cancer - Uncuta, Alina-Andreea
Molekular-Neurologische Abteilung
Reaktive Astrozytose im Mittelhirn bei chronisch-entzündlichen Darmerkrankungen - Wenkmann, Katharina
Strahlenklinik
EDIL3-driven immune exclusion and its impact on CD8⁺ T-cell proliferation and effector function in HNSCC
| Bodenmeier, Teresa Medizinische Klinik 1 | Tracking Multiple Sclerosis in the Gut: Unraveling Disease-Associated Patterns in the Fecal Vesiculome |
| Bolsinger, Sarah Nephropathologische Abteilung | Therapeutic potential of AKAP6 in nuclear enve-lopathies in striated muscle |
| Colotti, Jana Translational-Immunologische Abteilung | The functional role of glutaminyl cyclases in B cell activation and plasma cell differentiation |
| Dietrich, Vanessa Medizinische Klinik 3 | The impact of systemic inflammation on single cell osteoclast resorption in psoriatic arthritis |
| Fischer, Jule Institut für Physiologie und Pathophysiologie | Optimizing miRNA-dependent, light dependent mRNA-dependent mRNA regulation using PAL in Drosophila |
| Grünberg, Anna Maria Transfusionsmedizinische und Hämostaseologische Abteilung | ECP-treated lymphocytes alter the phenotype and function of human dendritic cells |
| Habura, Zuzanna Kinder- und Jugendklinik | Non-invasive evaluation of kidneys in patient with congenital anomalies of the kidney and urinary tract (CAKUT) using Ultrasound Localization Microscopy |
| Hosp, Daniel Strahlenklinik | The influence of ionizing radiation on the immunophenotype and functionality of B cells |
| Jasarevic, Hena Institut für Zelluläre und Molekulare Physiologie | Induction of fibrosis, t-system remodelling and myocardial dysfunction by inflammatory signals in an ex-vivo model of beating human myocardium |
| Ohnemüller, Michèle Translational-Immunologische Abteilung | The role of NGLY1 in healthy and pathogenic plasma cells |
| Puric, Julijana Institut für Physiologie und Pathophysiologie | The physiological function of BACE1 on tactile perception and global alterations in the synaptic transmission in the brain of BACE1 knockout mice |
| Privalov, Michael Molekulare und Experimentelle Chirurgie | Validation of predictive markers for therapy response in the treatment of metastatic CRC |
| Rödel, Eike Volkhard Institut für Biochemie | Experimental validation of algorithms finding new melanoma-promoting genes in nevi |
| Schedlbauer, Julia Institut für Physiologie und Pathopysiologie | Vergleichende Untersuchungen zur Reaktivität von Dimethylglyoxal und anderen bekannten reaktiven Dicarbonylverbindungen sowie hypoxischen Bedingungen |
| Schweigert, Alina Molekular-Neurologische Abteilung | Exploring the role of gut-derived extracellular vesi-cles in Parkinson’s disease progression |
| Simmich, Theresa Maria Radiologisches Institut | The Role of 3D Imaging in Enhancing the Accuracy of Radiofrequency Ablation for Liver Metastases: Impact on Recurrence Rates and Risks |
| Soreata, Briana-Maria Kinder- und Jugendklinik | Dynamic changes of stem cells and stem cellderived extracellular vesicles in human milk from mothers of premature babies |
| Strauss, Lara Mikrobiologisches Institut | Investigation of sex-differences in ILC2-adipocyte interaction using adipose tissue organoids |
| Subke, Hannah Nephropathologische Abteilung | The role of TPPP in the pathogenesis of chronic kidney disease |
| Vogel, Christian Molekular-Neurologische Abteilung | Analysis of regional immune cell activation in human postmortem tissue of IBD patients |
| Wagner, Frauke Institut für Zelluläre und Molekulare Physiologie | Effect of ADPKD-associated pore mutations on the ion channel function of polycystin-1/polycystin-2 heterotetramers |
| Weber, Sophia Kinder- und Jugendklinik | Multispectral optoacustic tomography for advanced imaging of centronuclear myopathy |
| Wenkel, Daria Institut für Physiologie und Pathophysiologie | BACE1-Substrate in der peripheren Somatosensorik: SEZ6- und Neuregulin-vermittelte Signalwege in Haut und Spinalganglien |
| Zubori, Helena-Katharina Medizinische Klinik 4 | Molecular elucidation of simultaneous COL4A4 and KANK1 variants in hereditary kidney disease |
Förderjahr 2024
| Baumgärtner, Lea Plastisch- und Handchirurgische Klinik | Development of biofabricated 3D breast cancer in a perfusion reactor as tumor angiogenesis and therapy model |
| Blunk, Hannah Medizinische Klinik 5 | Optimizing CAR T-cell manufacturing to reduce risk of production failure |
| Böllet, André Medizinische Klinik 1 | Metabolomic Profiling of Bacterial Extracellular Vesicles in Autoimmune Disorders: Optimizing Iso-lation and Characterization Techniques |
| Clausen, Finn-Niklas Chirurgische Klinik | Characterisation of human B-cell subsets and their role in the progression of Gastrointestinal cancer |
| Deckert, Lorenz Institut für Biochemie | Sox9 mediates mechanisms of neural stem cell decisions |
| Döll, Lukas Chirurgische Klinik | Breast tumour engineering in the arteriovenous loop model |
| Eisenack, Lea Institut für Anatomie | Impact of micro- and nanoplastic particles on the functionality of human macrophages |
| Egger-Hackenschmidt, Saskia Radiologisches Institut | Structured analysis of pancreatic lesions in radiological imaging using artificial intelligence |
| Görtz Lizarraga, Matthias Institut für Biochemie – Professur für Biochemie und Molekulare Neurowissenschaften | Unraveling the molecular impact of mechanical forces on lineage decision in derived 3D human brain organoids |
| Grodzki, Milena Experimentell-Therapeutische Abteilung | The role of glutaminyl-peptide cyclotransferaselike protein (QPTCL) in Pediatric Acute Lymphoblastic Leukemia (ALL) and other neoplasms in childhood and adolescence |
| Jasarevic, Hena Institut für Zelluläre und Molekulare Physiologie | Induction of fibrosis, t-system remodelling and myocardial dysfunction by inflammatory signals in an ex-vivo model of beating human myocardium |
| Keskiner-Kemerli, Melisa Kinder- und Jugendklinik | The in vivo effect of asciminib on bone and cartilage metabolism of zebra fish larvae compared to imatinib, dasatinib and bosutinib |
| Lange, Cuno Hautklinik | Relapse- and Therapy-Monitoring of metastasized Prostate Cancer using Protease activity measurements in plasma extracellular vesicles (pEV) |
| Mayr, Simon Radiologisches Institut | Cardiac imaging at Low-field MRI: A comparison of 0.55 T and 1.5 T |
| Menzl, Lynn Neurochirurgische Klinik | Spacial multi-omic and functional profiling of neural high and neural low glioblastoma |
| Moll, Leander Medizinische Klinik 3 | Tissue dependent function of adipocytes |
| Moser, Christina Medizinische Klinik 1 | Impact of neonatal fecal EVs on gut barrier function |
| Neuner, Laura Mikrobiologisches Institut | Effect of Itaconate and it’s isomers on bacterial and fungal pathogens |
| Pechmann, Leonie Molekular-Immunologische Abteilung | The role of the Aryl hydrocarbon receptor in the B-cell-mediated immune response in mice and humans |
| Reisinger, Chiara Kinder- und Jungendklinik | Non-invasive evaluation of graft condition in adult patients with kidney transplant using Multispectral Optoacoustic Tomography and Ultrasound Localization Microscopy |
| Rist, Carmen Medizinische Klinik 4 | Investigating the role of SERPINA1 related to the permeability of the glomerular filtration barrier in primary FSGS |
| Salein, Nina Chirurgische Klinik | Comparative analysis of subpopulation differentiation and pathogenic activities of fibroblasts in colorectal carcinoma and inflammatory bowel diseases. |
| Schäfer, Anna Strahlenklinik | Effects of DNA damage repair inhibitor-based molecular targeting of HNSCC combined with radiotherapy and immune checkpoint inhibition on T cell activity |
| Schrade, Jonas MCO BT – Fakultät für Biologie, Chemie und Geowissenschaften | The role of the endonuclease Zucchini in piRNA biogenesis in pluripotent stem cells |
| Seidel, Christina Hautklinik | Liquid biopsy for the detection of genetic altera-tions through Nanopore sequencing in uveal mela-noma |
| Sofokleous, Thaleia Kinder- und Jugendklinik | Characterization of a genetically altered CDC7-DBF4 Kinase as the cause of atypical bronchopul-monary dysplasia (BPD) |
| Steger, Lisa Medizinische Klinik 5 | Optimizing cytokine release of TRUCKs by pro-moter engineering |
| Steinsdörfer, Leonie Strahlenklinik | Impact of molecular targeting with DNA damage repair Inhibitors AZD0156 and VE-822 concomitant with hypo-fractionated radiotherapy on NK cell activity and cytotoxicity |
| Trottnow, Magnus Strahlenklinik | The immune modulatory effects of radiotherapy on the complement system |
| Veneris, Sophia Georgia Molekular-Neurologische Abteilung | The role of CD109 on extracellular vesicles |
| Weidt, Jonathan Kinder- und Jungendklinik | Characterization of physical properties of erythrocytes by deformability cytometry (DC) and proof of concept of DC as a diagnostic tool for the detection of hereditary spherocytosis |
| Wendler, Laura Chirurgische Klinik | Analysis of the impact of SPARCL1 on EMT |
| Weidenfeller, Martin Molekular-Neurologische Abteilung | Unveiling Gastrointestinal Alterations in Parkin-son’s Disease through Fecal Analysis |
Förderjahr 2023
| Birkmann, Lara Molekular-Immunologische Abteilung | The function of the N-glycanase 1 (NGLY-1) in B cell differentiation |
| Fuhrmann, Tobias Kinder- und Jugendklinik | The in vitro effect of asciminib on bone and cartilage metabolism |
| Gawor, Jule Mikrobiologisches Institut | Dysregulation of type 2 immune responses and microbiota in patients with obesity |
| Gehrke, Raffaela Psychiatrische und Psychotherapeutische Klinik | Interaction between sphingolipid and serotonergic systems of the brain in the mechanisms of alcohol instrumentalization of emotional state in mice |
| Giese, Sebastian Institut für Biochemie | Analysis of spatial neural stem cell activation patterns in the adult murine hippocampus. |
| Heininger, Hannah Medizinische Klinik 1 | Network excitability in a proteolytically inactive BACE1 mouse model |
| Hindermann, Johanna Medizinische Klinik 1 | Molecular and functional analysis of mTOR signalling pathway inhibition on regulatory T cell differentiation |
| Hobauer, Julia Medizinische Klinik 1 | Unraveling the Gut-Liver Axis: Investigating the transmission routes of bacteria-derived OMVs in Primary Sclerosing Cholangitis |
| Hoock, Linus Institut für Biochemie | Targeting autophagy to enhance neural stem cell function |
| Knorr, Sophie Hals-Nasen-Ohren-Klinik | Magnetically guided migration of SPION-loaded T cells through an endothelial barrier |
| Kramer, Katharina Plastisch- und Handchirurgische Klinik | Entwicklung und Testung einer Biotinte aus Mammagewebe zur Erforschung von Brustkrebs |
| Lauter, Luis Kinderherzchirurgische Abteilung | Development of an in vitro system for studying antigen-specific T cell responses |
| Leischner-Merk, Daria Hals-Nasen-Ohren-Klinik | Repolarisation of macrophages by superparamagnetic iron oxide nanoparticles |
| Loderbauer, Lisa Medizinische Klinik 4 | Medizinische Klinik 4 |
| Löffler, Lisa Hals-Nasen-Ohren-Klinik | Influence of nanoparticle-loading on effector functions of CAR-T cells and on cell death induction in target cells |
| Meusel, Leonie Sophie Hautklinik | Strategies to improve CD16 expression on natural killer cells after ex-vivo expansion |
| Miering, Tobias Institut für Physiologie und Pathophysiologie | Investigating the pathogenic potential of KCNH5 variants in neurodevelopmental disorders |
| Mundlos, Hanna Molekular-Neurologische Abteilung | Influence of chronic ileocolitis on hippocampal microglia and adult hippocampal neurogenesis in a mouse model of Crohn’s Disease |
| Nzirorera, Rayk Hautklinik | Influence of IVIg on human blood dendritic cells and their ability to induce T cell responses |
| Orthen, Hannah Molekular-Immunologischen Abteilung | Investigations on the effect of microplastics on B cell activation and plasma cell differentiation |
| Priller, Christina Institut für Physiologie und Pathophysiologie | Investigating the pathogenic potential of USP34 variants in neurodevelopmental disorders |
| Roth, David Chirurgische Klinik | The Role of SEMA4G in Pancreatic Cancer |
| Schön, Simon Pathologisches Institut | Development of a deep-learning algorithm to distinguish between low-grade dysplasia, high-grade dysplasia and adenocarcinoma in colorectal cancer |
| Schott, Christian Hautklinik | Protease measurement in plasma extracellular vesicles (pEV) in patients with prostate carcinoma for diagnostic and prognostic evaluation |
| Schwendner, Raphael Medizinische Klinik 1 | Contribution of bacterial membrane vesicles to intestinal barrier dysfunction |
| Sichel, Manuel Medizinische Klinik 2 | Investigation of endothelial glycocalyx (eGC) components as potential biomarkers of acute coronary syndrome and of shear stress induced eGC degradation |
| Sommerfeld, Lisa Radiologisches Institut | AI-training for automated extraction of imaging biomarkers of the heart and the great vessels in COVID-19 patients as a model for translational risk assessment |
| Speiseder, Jonas Neurologische Klinik | Impact of microplastic particle uptake by ingestion and inhalation on microplastic exposure to the human central nervous system |
| Stepansky, Leonard Radiologisches Institut | Automatic detection of adrenal gland incidentalomas |
| Tripp, Sonja Institut für Exp. u. Klinische Pharmakologie u. Toxikologie | Photoswitchable Glucose Inhibitors |
| Türkan, Kaan Radiologisches Institut | Development of an algorithm for cardiovascular risk stratification from non-triggered CT images. |
| Wesselmann, Florian Nephropathologische Abteilung | Complement mediated crosstalk between fibroblasts and macrophages in the development of a kidney fibrosis after transplantation |
| Wientjes, Peter Franz Virologisches Institut – Klinische und Molekulare Virologie | Mechanische Eigenschaften von T-Zellen unter Einfluss von Virusproteinen |
| Wolf, Ronny Kinder- und Jugendklinik | Enhancement of radiotherapy efficacy by inhibition of serine-glycine biosynthesis with NAMPT inhibi-tors in Ewing’s sarcoma |
| Wunder, Björn Plastisch- und Handchirurgische Klinik | Myogenic differentiation of Adipose-derived stem cells |
| Zagrada, Mrika Molekular-Immunologische Abteilung | The function of the glucose transporter type I in human antibody-secreting cells – Immune defects in GLUT1-DS patients? |
| Zeilmann, Markus Kinder- und Jugendklinik | Identification of additional variant carriers through MIP-assay based targeted re-sequencing in ARM and LUTO individuals in previously found putative genes |
| Zimmermann, Hendrik Neuropathologisches Institut | Circadian Genexpression of brain tissue from drug-resistant patients |
Förderjahr 2022
| Arnet, Lisa Hautklinik | The generation of neo-antigens recognized by T cells through manipulation of RNA splicing in tumor cells. |
| Azodanlou Delara Hautklinik | Ex-vivo expanded NK cells for treatment of uveal melanoma |
| Büttner Clara Medizinische Klinik 5 | Enhancing murine CAR T cell efficacy by improved expansion protocol and co-treatment strategies |
| Dashi Tobias Strahlenklinik | The impact of radiotherapy on immunogenic signaling pathways in head and neck squamous cell carcinoma cell lines |
| Düfel Leonore Stammzellbiologische Abteilung | Characterizing the effect of synuclein-mediated microglia stimulation on human neuronal cells |
| Edrich Lisa-Maria Medizinische Klinik 1 | Exploring the potential diagnostic potential of bacterial extracellular vesicles in Multiple Sclerosis |
| Einhaus Johanna Kinder- und Jugendklinik | General contribution of copy number variants (CNV) for the formation of lower urinary tract obstruction (LUTO). |
| Eiselt Jan Chirurgische Klinik | Analysis of the role of MAP3K7 in chemoresistance of pancreatic ductal adenocarcinoma |
| Englich Moritz Plastisch- und Handchirurgische Klinik | Influence of different patient data on the proliferation and differentiation capacity of human myoblasts |
| Geißler Simon Stammzellbiologische Abteilung | Mitochondriale Fusion / Fission und Signalverhalten in SPG7-Neuronen |
| Groh, Marie Molekulare und Experimentelle Chirurgie | Comparative studies of gene expression in primary tumors and metastases of colorectal carcinoma |
| Hofmann Thea Medizinische Klinik 3 | The role of Nrf1 (Nuclear respiratory factor 1) as a regulator of osteoclast metabolism and bone turnover |
| Karimi Bita Elisa Hautklinik | Protease measurement in plasma extracellular vesicles (pEV) in patients with primary and metastatic uveal melanoma for diagnostic and prognostic evaluation |
| Kißler Alicia Institut für Zelluläre und Molekulare Physiologie | Differential role of γ- and α-subunits in proteolytic ENaC activation |
| Krämer Florian Chirurgische Klinik | Role of the transcription factor Zeb1 in human pancreatic cancer-associated fibroblasts (CAFs) |
| Loderbauer Lisa Medizinische Klinik 4 | The role of the (collagen IV a345 molecule in the) distal renal tubule in Alport Syndrome |
| Lötzsch Chiara Inst. f. Biochemie-Lehrstuhl für Biochemie u. Mol. Medizin | Contribution of astrocytes subtypes in the human dentate gyrus to the pathology of temporal lobe epilepsy |
| Lüders, Anina Institut für Mikrobiologie – Klinische Mikrobiologie, Immunologie und Hygiene | Role of Plasmodium falciparum small variant surface antigens in modulating host cell function through extracellular vesicles |
| Nedoschill David Kinder- und Jugendklinik | Timing of metabolomic intervention with serine/glycine- biosynthesis pathway in combination with radiotherapy in Ewing sarcoma |
| Pfeuffer Ann-Katrin Institut für Zelluläre und Molekulare Physiologie | Mechanisms and regulating pathways of t-tubule membrane flux in human and animal ventricular cardiomyocytes |
| Roukhami Sofia Nephropathologische Abteilung | Modulation of urothelial carcinoma fatty acid metabolism to enhance ferroptosis in a zebrafish xenograft model |
| Sebald, Adrian Medizinische Klinik 1 | Characterizing the immune-modulatory properties of OMVs on Lymphocytes |
| Speer, Jasmin Molekular-Pneumologische Abteilung | The role of IL-6 on allergen and RV induced immune responses in asthma |
| Spießl, Kathrina Medizinische Klinik 5 | Characterization of tumor and immune cells in breast cancer organoids |
| Steenpaß Jana Pathologisches Institut | Prognostischer und prädiktiver Einfluss des HER2-Status beim invasiven Mammakarzinom – die Bedeutung einer niedrigen bzw. heterogenen HER2- Expression |
| Ünüvar Sumeyya Inst. f. Biochemie-Lehrstuhl für Biochemie u. Mol. Medizin | Molekulare Effekte von Ceramiden auf Normal- und Tumorzellen im Kontext der Behandlung mit kaltem atmosphärischen Plasma |
| Wachter Matthias Strahlenklinik | Immune-modulating potential of DNA damage repair inhibitors interfering with radiotherapy |
| Wangerin, Sarah Medizinische Klinik 5 | The role of micro-RNA mediated autophagy and the interplay between NPNT and autophagy in the pathogenesis of idiopathic membranous glomerulonephritis |
| Wattenbach Christian Plastisch- und Handchirurgische Klinik | Interaction of adipose-derived stem cells with breast cancer cells after breast-conserving therapy and irradiation – evaluation of oncological safety of autologous lipotransfer |
| Yankouskaya, Katharina Kinder- und Jugendklinik | Identification of immunoregulatory markers of juvenile autoimmune hepatitis predicting the therapy course |