IZKF-Retreat 2021

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Programme Thursday, 22 April 2021

 

Time

Room 1

Meeting-ID: 615 8708 7374
Password: room1

Room 2

Meeting-ID: 621 4095 0382
Password: room2

Room 3

Meeting-ID: 654 3311 7672
Password: room3

09:30 – 10:30

Keynote Lecture

Raubverleger, Pseudojournale und Scheinkonferenzen –
Nepper, Schlepper, Bauernfänger in der digitalen Wissenschaftswelt (I)
Prof. Dr. Olaf Gefeller
Institut für Medizininformatik, Biometrie und Epidemiologie (IMBE)

Meeting-ID: 615 8708 7374, Password: room1

 

Please be aware that the Keynote Lecture is held in German!

Alternative Programme

Paywall: The Business of Scholarship

(watch this video via vimeo)

10:45 – 11:45

Oncology

  • Expression and Function of CARs with alternative signaling domains (Leoni Albrecht)
  • The Role of DEAD-Box Helicase in Hepatocellular Carcinoma (Majken Appel)
  • Modulation of phenotype and effector function of macrophages after antibody dependent cellular phagocytosis (ADCP) (Alexander Biedermann)
  • Effects of an acidic tumor microenvironment on human melanoma (Chafia Chiheb)
  • Role of fibroblast polarization in the pathogenesis of colorectal carcinoma (Richard Demmler)
  • Metabolism, Tumor Microenvironment and Circulating Tumor-DNA in Ewing Sarcoma (Johanna Eiblwieser)

Immunology 

  • The role of STAT5 in the pathogenesis of chronic intestinal inflammation (Laura Besendorf)
  • Inhibition of CLR expression by IL-4 in human myeloid cells: functional effect on the response to mycobacteria (Niklas Blaha)
  • Stuying IBD related anti-trafficking agents using Single-cell RNA-sequencing (Mark Dedden)
  • Aberrant double-negative DNT-cells in patients with autoimmune lymphoproliferative syndrome (Nina Eisenhauer)
  • Role of Psen1 in intestinal epithelial homeostasis and inflammation (Lena Erkert)
  • Iota-Carrageenan, a natural polysaccharide from red algae, inhibits replication of SARS-CoV-2 (Maria Carolin Fröba)

Further

  • Estimation of Reference Intervals from Real-World Data (Tatjana Ammer)
  • Identification of disease related contraindications from prescription data alone (Wahram Andrikyan)
  • Electromagnetic tracking for advanced quality assurance in interstitial multi-catheter brachytherapy (Christopher Dürrbeck)
  • Boosting Random Effects (Colin Griesbach)
11:45 – 13:00 Break

(Room 1 can be used for conversations and exchange during the break)

13:00 – 14:00

Oncology

  • Zeb1 expression in stroma cells of pancreatic adenocarcinoma and its implications for tumorigenesis and metastasis (Isabell Frisch)
  • The role of ZEB1 in tumor-associated macrophages (Kathrin Fuchs)
  • Influence of DNA repair deficiency on radiation-modulated immunogenic properties of breast cancer cells (Simon Gehre)
  • Immunometabolic interplay in chronic myeloid leukemia: from immunosuppression to synthetic lethalit (Lukas Häselbarth)
  • The role of Neuritin-1 in melanomagenesis (Lucia Haller)
  • Semi-quantitatives Multidrug Monitoring von Kinase-Inhibitoren in einem Assay als Basis für zukünftige Expositionsabschätzungen bei vielen Patienten (Niklas Kehl)

Immunology

  • immunological and pathological parameters mediating RSV vaccine enhanced respiratory disease (Jana Fuchs)
  • The role of synovial macrophage subsets during rheumatoid arthritis (Hilal Garibagaoglu)
  • Regulators of IgA-mediated effector functions (Anna Gimpel)
  • Role of dendritic cell heterogeneity for the disease outcome in cutaneous Leishmania infection (Tobias Gold)
  • Assessing the antifungal activity of Robenidine against the human pathogenic mould Aspergillus fumigatus (Magdalena Grundler)
  • The role of the transcription factor PU.1 in lung cancer (Katja Hohenberger)

Further

  • Implementation of an AMTS-Stewardship at the Clinic in Fürth (Lea Jung-Poppe)
  • Risk prediction models for melanoma (Isabelle Kaiser)
  • Sedation in older patients (Sandra Kurkowski)
  • Statistical analysis of infectious disease spread (Junyi Lu)
  • Variable Selection in Bayesian Structured Additive Quantile Regression (Anja Rappl)

14:00 – 15:00

Keynote Lecture

Raubverleger, Pseudojournale und Scheinkonferenzen –
Nepper, Schlepper, Bauernfänger in der digitalen Wissenschaftswelt (II)
Prof. Dr. Olaf Gefeller
Institut für Medizininformatik, Biometrie und Epidemiologie (IMBE)

Meeting-ID: 615 8708 7374, Password: room1

 

Please be aware that the Keynote Lecture is held in German!

15:00 – 15:15

Break

(Room 1 can be used for conversations and exchange during the break)

15:15 – 16:15

Oncology

  • Analyses for changes in or differential regulation of the YAP/TAZ pathway in melanoma: understanding the escape from senescence (Viola Kluge)
  • Endogenous retroviruses drive tumor inflammation via RNA intermediates in bladder and ovarian cancer (Stefanie Köhler)
  • Role of DAPK1 in colorectal cancer (Philipp Kunze)
  • The impact of irradiation and lipotransfer on breast cancer (Chiara-Sophia Kutz)
  • Understanding differentiation and plasticity in melanoma – focus on microRNAs driving melanoma (Lisa Lämmerhirt)
  • Development of an digital twin in a hospital network (Daniel Lohmann)

Immunology

  • The preclinical charaterisation of the two thiopurine analoga G-04 and G-05 (Johannes Holle)
  • Functional analysis of the epigenetic regulator protein PfBDP1 during sexual differentiation in Plasmodium falciparum (Myriam Jeninga)
  • Understanding the metabolic regulation of gene expression in the human malaria parasite Plasmodium falciparum (Dominik John)
  • The role of Caspase-8 in pathogenesis of cholestatic liver diseases (Sophie Kaminski)
  • Impact of the metabolic enzyme ATP-citrate-lyase (ACLY) on the function of intestinal T-lymphocytes in the context of colitis-associated colon cancer (Selina Knittel)
  • Role of chemokine receptors in asthma (Susanne Krammer)

Further

  • Transport characteristics of L-arginine and its derivatives by cationic amino acid transporters (Sofna Banjarnahor)
  • Treatment of left ventricular hypertrophy by anti- FGFR4 antibody therapy (Luisa Daume)
  • Modeling AL amyloidosis in vitro: Pathological effects of light chains and AL protein states on renal and cardiac cells (Nathalie Krieglstein)
  • Regulation of PTPRO and it‘s miR-26b dependent Expression in podocytes (Carmen Popanda)
  • MAGI2 dependent LPA signaling in podocytes (Louis Rhode)

Programme Friday, 23 April 2021

Time

Room 1

Meeting-ID: 615 8708 7374
Password: room1

Room 2

Meeting-ID: 621 4095 0382
Password: room2

Room 3

Meeting-ID: 654 3311 7672
Password: room3

09:00 – 10:00

Oncology

  • Optimization of MRI for Radiotherapy (Siti Masitho)
  • The role of RNA-binding proteins in malignant melanoma (Tina Meißgeier)
  • Stablishment and screening of in vivo CRISPR-Cas9 in Pancreatic Cancer organoids (Maria Miquel)
  • Induction of tissue-resident memory T-cells against lung cancer (Friederike Oltmanns)
  • Phenotyping of breast lesions by using Radiomics to differentiate between benign and malignant lesions and to identify molecular tumor subtypes (Mona Pistel)
  • Transcriptional Regulation in Malignant Melanoma – Role of Sox21 (Nicole Rachinger)

 

Immunology

  • CD83 as key regulator during immune homeostasis and inflammation (Pia Langguth)
  • The role of IL3 and GPR15 in the IBD (Li-Juan Liu)
  • The pathogenetic role of tissue-resident memory T cells in acute Graft-versus-Host-Disease (Diana Matthe)
  • Functional characterization of TRM cells in inflammatory bowel diseases (Eva-Maria Paap)
  • Investigations on the sexual cycle of the human pathogenic mould Aspergillus fumigatus as potential virulence determinant (Tobias Pazen)
  • Donor-induced transplant tolerance by sCD83 after cornea transplantation (Katrin Peckert-Maier)

 

Further

  • Generation of novel 3D co-culture systems for study of glomerular functions ex vivo (Victoria Rose)
  • Hypoxic Regulation of Histon Lysine Demethylases in the Kidney (Carlotta Schönau)
  • Molecular characterization of late onset ciliopathy with chronic kidney disease caused by biallelic ANKS6 muta-tion (Hannah Schwarz)
  • Characterization of Polycystin-2 in Xenopus laevis oocytes (Tobias Staudner)
  • Molecular clarification of hereditary nephropathies with a tubulointerstitial phenotype (Florian Wopperer)

 

 

 

 

 

10:00 – 10:15

 Break

(Room 1 can be used for conversations and exchange during the break)

10:15 – 11:15

Oncology

  • Immunomonitoring during transarterial chemoembolization of hepactocellular carcinoma and correlation with clinical outcome (Jonas Schmid)
  • Role of Fibroblast Growth Factors in chronic liver diseases (Tatjana Seitz)
  • The molecular regulation of chondrogenesis and cartilage homeostasis by MIA/CD-RAP (Sebastian Stäbler)
  • The role of neutrophils in the development of metastasis in colorectal cancer (Antonia Stehr)
  • Beta-6-integrin in colorectal carcinoma: patho-functions and perspectives as a therapeutic target (Chiara van Passen)
  • The role of Zeb1 in providing cellular plasticity and EMT during pancreatic cancer formation (Ruthger van Roey)

Immunology

  • Development of a neutralizing antibody against SARS-CoV-2 (Antonia Sophia Peter)
  • Targeting draining lymph node scaffold cells to induce immune tolerance (Fabian Schälter)
  • The Fate of Lung Resident Memory T Cells (Anna Schmidt)
  • Regulatory interaction between cyclins and cytomegalovirus kinase pUL97: focus on pUL97 drug resistance mutations for the development of a novel antiviral strategy (Martin Schuetz)
  • Preclinical and clinical analysis of the mechanisms and efficacy of Ontamalimab (Lisa Lou Schulze)
  • Gut homing of monocytes and functional consequences for intestinal wound healing and inflammation (Katrin Sommer)

Further

  • Individualised nutritional intervention to tackle malnutrition in nursing home residents (Johanna Seemer)
  • Modulating the Rho-ROCK signaling pathway as a new therapeutic target for corneal endothelial diseases (Maria Strunz)
  • Problematic and contraindicated drug prescriptions in the hospitalic sector (Melanie Then)
  • Insights into Meibomian gland function (Ingrid Zahn)
  • Extending the Boosting Framework based on Bayesian Methodology (Boyao Zhang)

11:15 – 12:15

 Break

(Room 1 can be used for conversations and exchange during the break)

12:15 – 13:00

Oncology

  • The role of the NPY system in liver metastasis (Laura Wormser)
  • The role of ATF2 in 5FU (Hao Yang)
  • Molecular effects of cold atmospheric plasma on melanoma cells (Tom Zimmermann)

Immunology

  • Antimicrobial and immunomodulatory effects of sodium chlorosum (Julius Sommer)
  • Bone alterations in a mouse model of Cohn’s disease (Iris Stolzer)
  • New immunotherapies for lung cancer (Patrick Tausche)
  • The role of IL-3 in IBD (Karen Ullrich)
  • Phenotypic and transcriptional characterization of auto-reactive cells (Artur Wilhelm)

Further

  • Interstitial multicatheter brachytherapy of breast (Nadin Abu-Hossin)
  • MPE (Maya Shariff)
  • Burdens on caregivers of day care guests and nurses (Nadja Hofmann)

13:05 – 14:00

Feedback

(Feedback-Session in Room 1
Meeting-ID: 615 8708 7374
Password: room1)