{"id":6864,"date":"2023-04-26T15:50:47","date_gmt":"2023-04-26T13:50:47","guid":{"rendered":"https:\/\/www.izkf.med.fau.de\/?page_id=6864"},"modified":"2025-08-27T10:28:52","modified_gmt":"2025-08-27T08:28:52","slug":"n9-engineered-cells-in-skin-disease-bosch-voskens","status":"publish","type":"page","link":"https:\/\/www.izkf.med.fau.de\/en\/projekte\/jochen-kalden-foerderprogramm\/n9-engineered-cells-in-skin-disease-bosch-voskens\/","title":{"rendered":"N9 Engineered cells in skin disease (Voskens)"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">Dressing up and ready to move: Engineered immune cells for treatment of autoimmune skin diseases<\/h4>\n\n\n\n<p>Term: 01.07.2024 &#8211; 30.06.2027<\/p>\n\n\n\n<p>We hypothesize that, during inflammation, a highly motile subset of lymphocytes, including T cells, B cells and regulatory T cells migrates from the blood into the skin. The characterization of this highly motile subset would allow us to identify the migration and suppressive molecules selectively employed by these cells to reach the site of inflammation. We propose that we can engineere blood-derived immune cells with these molecules. In such a scenario, these engineered immune cells are highly migratory and ready to move to the site of inflammation after adoptive cell transfer.<\/p>\n\n\n\n<p>&nbsp;<\/p>\n\n\n<div class=\"fau-person thumb-size-small border\" itemscope itemtype=\"http:\/\/schema.org\/Person\">\n<div class=\"row\"><figure itemprop=\"image\" class=\"person-thumb\" aria-hidden=\"true\" role=\"presentation\" itemtype=\"http:\/\/schema.org\/ImageObject\"><a href=\"https:\/\/www.izkf.med.fau.de\/person\/prof-dr-caroline-j-bosch-voskens-phd\/\" tabindex=\"-1\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.izkf.med.fau.de\/files\/2022\/11\/Bosch-Voskens-120x160.jpg\" itemprop=\"contentUrl\" alt=\"Prof. Dr. Caroline J. Voskens PhD\" srcset=\"https:\/\/www.izkf.med.fau.de\/files\/2022\/11\/Bosch-Voskens-120x160.jpg 120w, https:\/\/www.izkf.med.fau.de\/files\/2022\/11\/Bosch-Voskens-240x320.jpg 240w\"><\/a><meta itemprop=\"identifier\" content=\"https:\/\/www.izkf.med.fau.de\/person\/prof-dr-caroline-j-bosch-voskens-phd\/\"><meta itemprop=\"width\" content=\"120\"><meta itemprop=\"height\" content=\"160\"><\/figure><div class=\"person-default-thumb\"><h3><a href=\"https:\/\/www.izkf.med.fau.de\/person\/prof-dr-caroline-j-bosch-voskens-phd\/\"><span itemprop=\"name\"><span itemprop=\"honorificPrefix\">Prof. Dr.<\/span> <span class=\"fullname\"><span itemprop=\"givenName\">Caroline J.<\/span> <span itemprop=\"familyName\">Voskens<\/span><\/span>, <span itemprop=\"honorificSuffix\">PhD<\/span><\/span><\/a><\/h3><div class=\"person-info\"><ul class=\"contactlist\"><li class=\"person-info-email email\"><span class=\"screen-reader-text\">E-Mail: <\/span><a itemprop=\"email\" href=\"mailto:caroline.bosch-voskens@uk-erlangen.de\">caroline.bosch-voskens@uk-erlangen.de<\/a><\/li><\/ul><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Dressing up and ready to move: Engineered immune cells for treatment of autoimmune skin diseases Term: 01.07.2024 &#8211; 30.06.2027 We hypothesize that, during inflammation, a highly motile subset of lymphocytes, including T cells, B cells and regulatory T cells migrates from the blood into the skin. The characterization of this highly motile subset would allow [&hellip;]<\/p>\n","protected":false},"author":1355,"featured_media":0,"parent":6825,"menu_order":9,"comment_status":"closed","ping_status":"closed","template":"page-templates\/page-subnav.php","meta":{"_rrze_cache":"enabled","_access_permission":"","_rrze_multilang_single_locale":"en_GB","_rrze_multilang_single_source":"https:\/\/www.izkf.med.fau.de\/?page_id=6862","footnotes":""},"page_category":[],"page_tag":[],"workflow_usergroup":[],"class_list":["post-6864","page","type-page","status-publish","hentry","en-GB"],"_links":{"self":[{"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/pages\/6864","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/users\/1355"}],"replies":[{"embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/comments?post=6864"}],"version-history":[{"count":6,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/pages\/6864\/revisions"}],"predecessor-version":[{"id":108200,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/pages\/6864\/revisions\/108200"}],"up":[{"embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/pages\/6825"}],"wp:attachment":[{"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/media?parent=6864"}],"wp:term":[{"taxonomy":"page_category","embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/page_category?post=6864"},{"taxonomy":"page_tag","embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/page_tag?post=6864"},{"taxonomy":"workflow_usergroup","embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/workflow_usergroup?post=6864"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}