{"id":21520,"date":"2023-12-11T14:01:51","date_gmt":"2023-12-11T13:01:51","guid":{"rendered":"https:\/\/www.izkf.med.fau.de\/?page_id=21520"},"modified":"2025-07-28T11:39:11","modified_gmt":"2025-07-28T09:39:11","slug":"n10-lamp1-neutrophils-in-lupus-nephritis-grieshaber-bouyer","status":"publish","type":"page","link":"https:\/\/www.izkf.med.fau.de\/en\/projekte\/jochen-kalden-foerderprogramm\/n10-lamp1-neutrophils-in-lupus-nephritis-grieshaber-bouyer\/","title":{"rendered":"N10 LAMP1+ neutrophils in lupus nephritis (Grieshaber-Bouyer)"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">LAMP1+ neutrophils in lupus nephritis<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Term: 01.07.2024 &#8211; 30.06.2027<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">My preliminary data highlight that neutrophil phenotypes define distinct SLE patients and that LAMP-1 is a strongly dysregulated protein in SLE. I hypothesize that LAMP1 expression defines a distinct activation state of neutrophils associated with a clinical subgroup of SLE patients with more severe kidney involvement. Hence, this project aims to study the functional<br>role of LAMP1 in neutrophils and probe associations of LAMP1 expression and serum levels with clinical features in SLE.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">&nbsp;<\/p>\n\n\n<div class=\"fau-person thumb-size-small border\" itemscope itemtype=\"http:\/\/schema.org\/Person\">\n<div class=\"row\"><figure itemprop=\"image\" class=\"person-thumb\" aria-hidden=\"true\" role=\"presentation\" itemtype=\"http:\/\/schema.org\/ImageObject\"><a href=\"https:\/\/www.izkf.med.fau.de\/person\/prof-dr-med-ricardo-grieshaber-bouyer\/\" tabindex=\"-1\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.izkf.med.fau.de\/files\/2023\/12\/Grieshaber-Bouyer-scaled-e1709216525580-120x160.jpg\" itemprop=\"contentUrl\" alt=\"Prof. Dr. med. Ricardo Grieshaber-Bouyer\" srcset=\"https:\/\/www.izkf.med.fau.de\/files\/2023\/12\/Grieshaber-Bouyer-scaled-e1709216525580-120x160.jpg 120w, https:\/\/www.izkf.med.fau.de\/files\/2023\/12\/Grieshaber-Bouyer-scaled-e1709216525580-240x320.jpg 240w\"><\/a><meta itemprop=\"identifier\" content=\"https:\/\/www.izkf.med.fau.de\/person\/prof-dr-med-ricardo-grieshaber-bouyer\/\"><meta itemprop=\"width\" content=\"120\"><meta itemprop=\"height\" content=\"160\"><\/figure><div class=\"person-default-thumb\"><h3><a href=\"https:\/\/www.izkf.med.fau.de\/person\/prof-dr-med-ricardo-grieshaber-bouyer\/\"><span itemprop=\"name\"><span itemprop=\"honorificPrefix\">Prof. Dr.<\/span> <span class=\"fullname\"><span itemprop=\"givenName\">Ricardo<\/span> <span itemprop=\"familyName\">Grieshaber-Bouyer<\/span><\/span><\/span><\/a><\/h3><div class=\"person-info\"><ul class=\"contactlist\"><li class=\"person-info-email email\"><span class=\"screen-reader-text\">E-Mail: <\/span><a itemprop=\"email\" href=\"mailto:ricardo.grieshaber@fau.de\">ricardo.grieshaber@fau.de<\/a><\/li><\/ul><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>LAMP1+ neutrophils in lupus nephritis Term: 01.07.2024 &#8211; 30.06.2027 My preliminary data highlight that neutrophil phenotypes define distinct SLE patients and that LAMP-1 is a strongly dysregulated protein in SLE. I hypothesize that LAMP1 expression defines a distinct activation state of neutrophils associated with a clinical subgroup of SLE patients with more severe kidney involvement. [&hellip;]<\/p>\n","protected":false},"author":1355,"featured_media":0,"parent":6825,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"page-templates\/page-subnav.php","meta":{"_rrze_cache":"enabled","_access_permission":"","_rrze_multilang_single_locale":"en_GB","_rrze_multilang_single_source":"https:\/\/www.izkf.med.fau.de\/?page_id=21516","_faue_teaser_image_id":0,"footnotes":""},"page_category":[],"page_tag":[],"workflow_usergroup":[],"class_list":["post-21520","page","type-page","status-publish","hentry","en-GB"],"faue_teaser_image_url":"","_links":{"self":[{"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/pages\/21520","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/users\/1355"}],"replies":[{"embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/comments?post=21520"}],"version-history":[{"count":5,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/pages\/21520\/revisions"}],"predecessor-version":[{"id":103921,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/pages\/21520\/revisions\/103921"}],"up":[{"embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/pages\/6825"}],"wp:attachment":[{"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/media?parent=21520"}],"wp:term":[{"taxonomy":"page_category","embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/page_category?post=21520"},{"taxonomy":"page_tag","embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/page_tag?post=21520"},{"taxonomy":"workflow_usergroup","embeddable":true,"href":"https:\/\/www.izkf.med.fau.de\/wp-json\/wp\/v2\/workflow_usergroup?post=21520"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}