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Interdisciplinary Center for Clinical Research
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  1. Friedrich-Alexander-Universität
  2. Medizinische Fakultät

Interdisciplinary Center for Clinical Research

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Archive Junior Projects

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Archive Junior Projects

J01: Hüffmeier, Institute of Human Genetics
Copy number polymorphisms as genetic risk factors for psoriatic arthritis
Term: 01.01.2010 – 31.12.2011

J12: Waldner, Department of Medicine 1
The role of hypoxia inducible factor‑1 during the pathogenesis of colitis‑associated cancer
Term: 13.03.2011 – 12.03.2013

J20: Fürnrohr, Department of Medicine 3
Functional analysis of the coding variant rs1143679 (R77H) in CD11bH) in CD11b
Term: 01.11.2011 – 15.08.2013

J21: Winkelmann, Department of Molecular Immunology
Function of KLF2 and 4 in B cell differentiation
Term: 01.01.2012 – 31.12.2013

J22: Jochmann, Department of Surgery
The role of O-GlcNAc-modification in regulating KSHV gene expression and replication
Term: 01.11.2011 – 31.10.2013

J27: López-Posadas, Department of Medicine 1
Impact of posttranslational protein geranylgeranylation in intestinal epithelial cells in gut homeostasis.
Term: 01.11.2012 – 31.10.2014

J28: Leppkes, Department of Medicine 1
Pathomechanisms of inflammation dependent fibrogenesis
Term: 16.11.2012 – 15.11.2014

J29: Beyer, Department of Medicine 3
Interaction of morphogene pathways in the development of fibrotic diseases
Term: 01.10.2012 – 30.09.2014

J30: Thomas, Institute of Clinical and Molecular Virology
Characterization of cytoplasmic activities of human cytomegalovirus pUL69 and its putative role as an antagonist of intrinsic immunity
Term: 01.01.2013 – 31.12.2014

J37: Bosch-Voskens, Department of Dermatology
Adoptive cell therapy with ex-vivo expanded NK and γδT cells in metastatic melanoma
Term: 01.07.2013 – 30.04.2016

J38: Dietel, Department of Medicine 2
MCS-18 for the treatment of atherosclerosis
Term: 01.02.2014 – 31.01.2016

J39: Dees, Department of Medicine 3
Hypermethylation of SOCS3 in fibrotic diseases
Term: 01.01.2014 – 31.12.2015

J40: Ramming, Department of Medicine 3
PU.1 signalling in fibrotic diseases
Term: 01.01.2014 – 31.12.2015

J41: Schauer, Department of Medicine 3
Neutrophil-induced resolution of inflammation in gouty arthritis
Term: 01.12.2013 – 30.11.2016

J43: Mchedlidze, Department of Medicine 1
The role of IL-33/ST2 signaling in the development of infectious colitis
Term: 01.02.2015 – 31.10.2016

J44: Hahn, Institute of Clinical and Molecular Virology
Rhadinovirus Entry Receptors
Term: 01.04.2015 – 31.12.2015

J45: Reuter, Institute of Clinical and Molecular Virology
Modulation der PRC2 Aktivität durch HCMV IE2
Term: 01.01.2015 – 30.06.2018

J50: Katharina Gerlach, Department of Medicine 1
IL-9 in CAC
Term: 16.10.2015 -15.04.2018 (bonus time until 15.10.2018)

J56: Palumbo-Zerr, Department of Medicine 3
Epigenetic reprogramming of macrophages
Term: 01.01.2017 – 30.06.2019

J57: Florian Full, Institute of Clinical and Molecular Virology
Herpesviruses and DUX4
Term: 01.01.2017 – 30.06.2019 (bonus time until 31.12.2019)

J62: Anika Grüneboom, Department of Medicine 3
Neutrophils in rheumatoid arthritis
Term: 01.08.2017 – 31.01.2020

J63: Sebastian Zundler, Department of Medicine 1
IL-3 in inflammatory bowel disease
Term: 01.12.2017 – 31.05.2020 (bonus time until 30.11.2020)

J69: Christiane Krystelle Nganou Makamdop, Institute of Virology
Effect of HIV on pre-existing vaccine immunity
Term: 01.09.2018 – 28.02.2021, Extension maternity leave: 01.05.21-31.08.21

J83: Ingo Ganzleben, Department of Medicine 1
Role of ferroptosis in inflammatory lung diseases
Term: 01.10.2020 – 31.11.2021

J77: René Pfeifle, Department of Medicine 3
Characterization of autoreactive B cells during RA
Term: 01.11.2019 – 30.04.2022

J78: Barbara Ruder, Department of Medicine 1
Role of ferroptosis during microbial infection
Term: 01.10.2019 – 15.02.2022

J76: Katerina Kachler, Department of Medicine 3
The role of itaconate in osteoclasts
Term: 16.10.2019 – 15.04.2022

J79: Christian Schwartz, Institute of Clinical Microbiology, Immunology and Hygiene
PD-L1 function during obesity and dysbiosis
Term: 01.09.19-28.02.2022 (bonus time until 31.08.2022)

J84: Sascha Kretschmann, Department of Medicine 5
Direct vs. indirect class II antigen presentation
Term: 01.11.2020 – 30.04.2023

J85: Kristina Scheibe, Department of Medicine 1
Cell-type-specific roles of IL36 in the Intestine
Term: 16.11.2020 – 15.05.2023 (bonus time until 15.11.2023)

J86: Heike Knott, Department of Medicine 1
Virome/macrophage interaction in Crohn’s disease
Term: 01.01.2021 – 30.06.2022

J87: Stefan Uderhardt, Department of Medicine 3
Stromal Network Communication in the Regulation of Immune Homeostasis
Term: 01.01.2021 – 30.06.2023

J90: Darja Andreev, Department of Medicine 3
The impact of Eos on bone loss
Term: 01.01.2022 – 30.06.2024

J91: Jean-Philippe Auger, Department of Medicine 3
Glucocorticoid-induced macrophage reprogramming
Term: 01.01.2022 – 30.06.2024

J07: Knippertz, Department of Immune Modulation
Adenovirus-mediated expression of therapeutic transgenes in human dendritic cells under the control of the CD83-promoter
Term: 01.09.2009 – 31.08.2011

J08: Rau, Institute of Pathology
Epigenetic regulation of the gastric inflammation-metaplasia-carcinoma-sequence by promotor methylation
Term: 01.10.2009 – 30.09.2011

J09: Hadjihannas, Experimental Medicine II
Impact of Conductin degradation by the Anaphase Promoting Complex (APC/C) on Wnt/b-catenin signaling during the cell cycle of colon cancer cells
Term: 01.01.2010 – 31.12.2011

J10: Wacker, Experimental Medicine II
Activin B as potential inducer of tumor stem cells in clear cell renal cell carcinoma
Term: 17.11.2009 – 16.11.2011

J18: Bruns, Department of Medicine 5
Immunmodulatory function of macrophages in tumor stroma of high malignant Burkitt lymphoma
Term: 01.02.2011 – 31.01.2013

J19: Britzen-Laurent, Department of Surgery
Immune escape in colorectal carcinoma: role of the IFN-g pathway
Term: 15.02.2011 – 14.02.2013

J24: Mougiakakos, Department of Medicine 5
Immune modulatory effects by oxidative stress in patients with chronic lymphatic leukemia
Term: 15.09.2011 – 14.09.2013

J25: Boos, Department of Plastic and Hand Surgery
Establishing of an autonomous lymphatic vessel network in the AV-loop model using lymnphatic endothelial cells and mesenchymal stem cells
Term: 01.02.2012 – 31.01.2014

J26: Kreß, Institute of Clinical and Molecular Virology
Regulation of the tumor marker Fascin by the oncoprotein Tax of Human T-cell lymphotropic virus type 1 (HTLV-1)
Term: 01.01.2012 bis 31.12.2013

J34: Kremer, Department of Medicine 5
Indirect presentation of HLA class II restricted tumor antigens
Term: 15.08.2012 – 14.08.2014

J35: Moskalev, Institute of Pathology
The role of long non-coding RNAs from human HOX loci in aberrant epi-genetic programming of gastrointestinal stromal tumours (GIST)
Term: 01.12.2012 – 30.11.2014

J47: Bach, Department of Medicine 5
Post-transcriptional regulation by Hoxa9
Term: 01.03.2015 – 31.08.2017

J54: Lehmann, Department of Dermatology
Alternative mechanisms of tumor rejection
Term: 01.11.2015 – 30.04.2018 (bonus time until 31.10.2018)

J55: Dietrich, Institute of Biochemistry
MicroRNA-188-5p in Hepatocellular Carcinoma
Term: 01.01.2016 – 30.06.2018 (bonus time until 31.12.2018)

J58: Dominic Bernkopf, Chair of Experimental Medicine II
Counteracting Wnt signaling
Term: 01.09.2016 – 28.02.2019 (bonus time until 31.08.2019)

J59: Fabian Müller, Department of Medicine 5
Immunotoxin induced anti-tumor immunity
Term: 01.07.2017 – 31.12.2019 (bonus time until 30.06.2020)

J67: Regina Jitschin, Department of Medicine 5
Metabolic reprogramming of AML MDSCs
Term: 01.01.2018 – 30.06.2021

J68: Jay Patankar, Department of Medicine 1
Regulation of intestinal epithelial Differentiation in mucosal inflammation and helaing
Term: 01.10.2017 – 31.03.2020

J73: Clara Tenkerian, Department of Surgery
Intracellular signaling by SPARCL1 in colon cancer
Term: 16.09.2018 – 30.06.2020

J80: Mousumi Mahapatro, Department of Medicine 1
Psen1 in colorectal cancer
Term: 01.05.2020 – 31.12.2020

J96: Maria de los Reyes Gamez Belmonte, Department of Medicine 1
Bace1/Bace2 in colorectal cancer development
Term: 01.10.2021 – 31.03.2024 (bonus time until 30.09.3024)

J97: Benedikt Jacobs, Department of Medicine 5
Immune-metabolic dysfunction of NK cells
Term: 01.01.2022 – 30.06.2024

J05: Grömer, Department of Psychiatry and Psychotherapy
Axonal transport and synaptic capture of proteins linked to Alzheimer’s disease
Term: 16.08.2009 – 15.08.2011

J06: Waschbisch, Department of Neurology
MicroRNA expression profiling of T cells derived from multiple sclerosis patients and healthy donors
Term: 01.01.2010 – 31.12.2011

J17: Dahlhaus, Institute of Biochemistry
The human and the murine Scal –two orthologs of a novel protein with diffrent protein interaction motifs and with relevance for the Fragile X Syndrome
Term: 15.02.2011 – 14.02.2013

J32: Abdallah, Department of Molecular Neurology
Molecular and structural analysis of neuropsychiatric symptoms in transgenic models of Parkinson’s disease
Term: 01.09.2012 – 31.08.2014

J33: Reiprich, Institute of Biochemistry
Sox2 in the CNS: regulating myelination by microRNAs
Term: 01.02.2013 – 31.01.2015

J46: Küspert, Institute of Biochemistry
The role of Zfp276 in glial development
Term: 01.04.2015 – 30.09.2017

J51: Marxreiter, Department of Neurology
Inflammatory signature in Parkinson’s disease
Term: 01.10.2015 – 31.03.2019

J52: Martin Regensburger, Department of Neurology
Neuronale Proliferation in SPG11-HSP
Term: 01.11.2015 – 30.04.2018

J53: Schmidt, Department of Neuroradiology
DTI in pseudoexfoliation glaucoma
Term: 03.08.2015 – 02.02.2018

J66: Esther Eberhardt, Department of Anesthesiology
ß subunits: adding pieces to the puzzle of pain
Term: 01.01.2018 – 31.08.2020

J74: Seda Salar, Department of Psychiatry and Psychotherapy
CtBP1 and neuronal excitability
Term: 01.02.2019 – 31.07.2021

J88: Florian Krach, Department of Stem Cell Biology
new RNA-binding proteins in sporadic ALS
Term: 16.11.2020 – 15.05.2023

J92: Alana Hoffmann, Division of Molecular Neurology
Neuron-Mikroglia Interaktion in MSA
Term: 01.07.2021 – 31.12.2021

J93: Liubov Kalinichenko, Department of Psychiatry and Psychotherapy
Lipids and Serotonin in drug instrumentalization
Term: 01.01.2022 – 30.06.2024 (bonus time until 31.12.2024)

Patrick Süß, Department of Molecular Neurology
Neuroinflammation and synucleinopathy in IBD
Term: 01.12.2021 – 30.11.2024

J95: Franziska Thiele, Institute of Biochemistry
Role of Tip60 in the PNS
Term: 01.01.2022 – 30.06.2024

J02: Raaz-Schrauder, Department of Medicine 2
The role of Fcg receptors on the formation and destabilisation of atherosclerotic
Term: 01.01.2010 – 31.12.2011

J03: Buchholz, Department of Medicine 4
The role of HIF-1α in genesis, cystic proliferation and epithelial-mesenchymal-transition of renal tubular epithelial cells – studies in a threedimensional in vitro
Term: 01.01.2010 – 31.12.2011

J04: Benz, Department of Paediatrics and Adolescent Medicine
Cardiovascular and renal changes in obesity – Influence of low nephron number
Term: 01.01.2010 – 31.12.2011

J13: Freisinger, Department of Medicine 4
Tonic afferent renal neurons: The role of TTX-sensitive sodiumchannels
Term: 01.01.2011 – 31.12.2012

J14: Kopp, Department of Medicine 4
23Sodium-MRI as new diagnostic tool to assess Na+-accumulation in therapy refractory hypertension
Term: 01.04.2011 – 31.03.2013

J15: Schmidt, Department of Plastic and Hand Surgery
Impact of cell-cell-communication and biomodulating agents on the formation of a neovascular in vivo system during exposure to ionizing radiation
Term: 15.03.2011 – 14.03.2013

J16: Härteis, Department of Cellular and Molecular Physiology
Activation of the epithelial sodium channel (ENaC) by plasmin,
trypsin IV and cathepsin S
Term: 01.01.2011 – 31.12.2012

J23: Hackenbeck, Department of Medicine 4
The role of the hypoxia-inducible factor (HIF) and lysyl oxidases in renal fibrosis
Term: 15.11.2011 – 11.08.2013

J31: Schödel, Department of Medicine 4
Function of a novel, HIF-regulated transcript
Term: 01.02.2013 – 31.01.2015

J52: Martin Regensburger, Department of Neurology
Neuronal proliferation in SPG11-HSP
Term: 01.11.2015 – 30.04.2018 (bonus time until 31.12.2018)

J65: Thomas Seidel, Institute of Cellular and Molecular Physiology
T-System Regulation by Glucocorticoids
Term: 01.11.2017 – 30.04.2020

J64: Steffen Grampp, Department of Medicine 4
Nephroprotection by HIF-hydroxylase inhibitors
Term: 01.10.2017 – 30.09.2019; 01.03.2019 – 31.08.2020 (bonustime bis 28.02.2021)

J70: Tilman Jobst-Schwan, Department of Medicine 4
Gene discovery in kidney disease
Term: 01.10.2018 – 31.03.2021 (bonus time until 30.09.2021)

J71: Andre Kraus, Department of Medicine 4
P2Y2R-dependent cyst growth in ADPKD
Term: 01.01.2019 – 30.06.2021

J36: Kremer, Department of Medicine 1
Identification of molecular signalling pathways in cholestatic pruritus
Term: 01.09.2013 – 31.08.2015

J42: Ferrazzi, Institute of Human Genetics
Bayesian reverse engineering of gene regulatory networks in heart development
Term: 01.04.2014 – 31.03.2016

J48: Scholtysek, Department of Medicine 3
PPARβ/δ in the crosstalk of bone and glucose metabolism
Term: 01.01.2015 – 30.06.2017

J60: Jung-Hyun Lee, Department of Dermatology
The role of Hck/Lyn in Vesicles secretion
Term: 01.10.2016 – 30.04.2018

J11: Schmid, Insitute of Medical Informatics
E.BOOST – Extending Boosting Methods and Competitors to New Settings of High-Dimensional Data
Term: 01.01.2010 – 31.12.2011

J49: Mayr, Insitute of Medical Informatics
Erweiterung von statistischen Boosting Algorithmen für die biomedizinische Forschung
Term: 01.04.2015 – 30.09.2017

J61: Elisabeth Waldmann, Department of Medical Informatics, Biometry and Epidemiology
Extending joint models in biomedical outcomes
Term: 01.01.2017 – 30.06.2019 (bonus time until 31.12.2019)

75: Sebastian Meyer, Institute of Medical Informatics, Biometry and Epidemiology
Statistical Analysis of Infectious Disease Spread
Term: 16.10.2018 – 15.04.2021 (bonus time until 15.10.2021)

J82: Chih-Wei Chen, Department of Medicine 3
O-GlcNAcylation regulates osteoclastogenesis
Term: 01.01.2020 – 31.12.2020

J81: Samir Jabari, Institute of Neuropathology
Web based Brain Tumor Image Classifier (WeB-TIC)
Laufzeit: 01.01.2020 – 30.06.2022 (bonus time until 31.12.2022)

J89: Adrian Regensburger, Department of Pediatric and Adolescent Medicine
MSOT imaging of strictures in Crohn’s disease
Term: 01.01.2021 – 30.09.2023 (bonus time until 31.03.2024)

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IZKF-Geschäftsstelle

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